Understanding Ocular Findings and Manifestations of Systemic Lupus Erythematosus: Update Review of the Literature

Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease. Up to one-third of patients suffering from SLE have various ocular manifestations. The ocular findings may represent the initial manifestation of the systemic disease and may lead to severe ocular complications, and even...

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Bibliographic Details
Published in:International journal of molecular sciences 2022-10, Vol.23 (20), p.12264
Main Authors: Luboń, Wojciech, Luboń, Małgorzata, Kotyla, Przemysław, Mrukwa-Kominek, Ewa
Format: Article
Language:English
Subjects:
autoimmune
Autoimmune diseases
Biopsy
Chronic conditions
Dermatitis
Disease
Edema
Erythema
Immunosuppressive agents
Inflammation
Literature reviews
Lupus
Medical personnel
ocular complications
Optic nerve
Patients
Review
Signs and symptoms
Skin
Systemic lupus erythematosus
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Description
Summary:Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease. Up to one-third of patients suffering from SLE have various ocular manifestations. The ocular findings may represent the initial manifestation of the systemic disease and may lead to severe ocular complications, and even loss of vision. Ocular manifestations are often associated with degree of systemic inflammation, but also can precede the occurrence of systemic symptoms. Early diagnosis and adequate management of patients with SLE are crucial and require cooperation between various specialists. Proper preparation of ophthalmologists can help to differentiate between complication of SLE and other ocular disorders. New therapies for SLE are promising for potential benefits, however, ocular side effects are still unknown.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms232012264