Synthesis and characterization of carboxymethyl chitosan nanogels for swelling studies and antimicrobial activity

Nanogels of a binary system of carboxymethyl chitosan (CMCh) and poly- (vinyl alcohol) PVA, were successfully synthesized by a novel in situ process. They were also characterized by various analytical tools like Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) a...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2012-12, Vol.18 (1), p.190-203
Main Authors: Farag, Reem K, Mohamed, Riham R
Format: Article
Language:English
Subjects:
Alcohol
Anti-Infective Agents - chemical synthesis
Anti-Infective Agents - chemistry
antimicrobial activity
Antimicrobial agents
Aspergillus flavus - drug effects
Biomedical materials
Candida albicans - drug effects
carboxymethyl chitosan
Chitosan - analogs & derivatives
Chitosan - chemical synthesis
Escherichia coli - drug effects
Fourier transforms
Gels - chemical synthesis
Hydrogels
Microscopy, Electron, Transmission
nanogels
Nanoparticles
Nanostructures - chemistry
Physical properties
poly(vinyl alcohol)
Polymers
Polyvinyl Alcohol - chemical synthesis
Spectrophotometry, Infrared
Spectroscopy, Fourier Transform Infrared
Staphylococcus aureus - drug effects
Surfactants
swelling ability
Tissue engineering
Toxicity
Trends
X-Ray Diffraction
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Summary:Nanogels of a binary system of carboxymethyl chitosan (CMCh) and poly- (vinyl alcohol) PVA, were successfully synthesized by a novel in situ process. They were also characterized by various analytical tools like Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and X-ray diffraction (XRD). They were studied for their unique swelling properties in water and different pH solutions. They were also investigated for their great ability to capture or isolate bacteria and fungi from aquatic environments.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules18010190