Tuberculosis infection in rural labor migrants in Shenzhen, China: Emerging challenge to tuberculosis control during urbanization

During China’s urbanization process, rural labor migrants have been suggested to be one important bridge population to change urban-rural distribution on tuberculosis (TB) burden. Aiming to estimate the prevalence of TB infection and to track the active disease development in rural labor migrants, a...

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Bibliographic Details
Published in:Scientific reports 2017-06, Vol.7 (1), p.4457-8, Article 4457
Main Authors: Li, Xiangwei, Yang, Qianting, Feng, Boxuan, Xin, Henan, Zhang, MingXia, Deng, Qunyi, Deng, Guofang, Shan, Wanshui, Yue, Jianrong, Zhang, Haoran, Li, Mufei, Li, Hengjing, Jin, Qi, Chen, Xinchun, Gao, Lei
Format: Article
Language:English
Subjects:
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Bacillus Calmette-Guerin vaccine
BCG
Humanities and Social Sciences
Infections
Interferon
Migrants
multidisciplinary
Population studies
Rural areas
Science
Science (multidisciplinary)
Smoking
Tuberculosis
Urbanization
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Summary:During China’s urbanization process, rural labor migrants have been suggested to be one important bridge population to change urban-rural distribution on tuberculosis (TB) burden. Aiming to estimate the prevalence of TB infection and to track the active disease development in rural labor migrants, a prospective study was conducted in Shenzhen city, southern China. TB infection was detected using interferon-γ release assay (IGRA). Here we mainly report the characteristics of TB infection in the study population based on the baseline survey. A total of 4,422 eligible participants completed baseline survey in July 2013. QuantiFERON (QFT) positivity rates 17.87% (790/4,422) and was found to be consistent with the local TB epidemic of the areas where the participants immigrated from. Age, smoking, residence registered place, and present of BCG scars were found to be independently associated with QFT positivity. Additionally, evidence for interaction between smoking and age was observed (p for likelihood ratio test 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-017-04788-1