Early hepatocellular carcinoma developed within dysplastic nodule as nodule-within-nodule appearance: Case report with literature review

Close follow-up of patients with liver cirrhosis has led to increased detection of hepatocellular carcinoma (HCC) at an early stage, especially with magnetic resonance imaging (MRI) innovations. We report the case of a 70-year-old man, with a recent history of liver cirrhosis due to chronic hepatiti...

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Bibliographic Details
Published in:Radiology case reports 2022-11, Vol.17 (11), p.4087-4090
Main Authors: Aassouani, Farid, Lkharrat, Fatima-Zahra, Charifi, Yahya, Attar, Aicha, Lahlali, Maria, El Bouardi, Nizar, Abid, Hakima, Haloua, Meryem, Alami, Badreeddine, Boubbou, Meriem, Maaroufi, Mustapha, Lamrani, Moulay Youssef Alaoui
Format: Article
Language:English
Subjects:
Case Report
Chemoembolization
Dysplastic nodule
Early HCC
Nodule-within-nodule
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Summary:Close follow-up of patients with liver cirrhosis has led to increased detection of hepatocellular carcinoma (HCC) at an early stage, especially with magnetic resonance imaging (MRI) innovations. We report the case of a 70-year-old man, with a recent history of liver cirrhosis due to chronic hepatitis C virus (HCV) complicated by hepatocellular carcinoma (HCC), and for whom trans-arterial chemoembolization (TACE) was planned, as the patient was assigned Child B7 at admission. Angiography performed during the first TACE cycle shows not only the “tumor blush” corresponding to previously detected HCC but also an additional small foci of HCC uptake seen within a large dysplastic nodule giving the appearance of “nodule-within-nodule.” Early detection of hepatocellular carcinoma improves prognosis. Hence, it is essential to be aware of all early aspects of HCC, including the nodule-within-nodule appearance on cross-sectional imaging, and also in angiography, as in this case.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2022.07.109