Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?

During the first half of 2022, the World Health Organization reported an outbreak of acute severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from the United Kingdom (UK) where a cluster of cases was first observed in previously well children aged

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Bibliographic Details
Published in:Frontiers in pharmacology 2022-11, Vol.13, p.1062408
Main Authors: Matthews, Philippa C, Campbell, Cori, Săndulescu, Oana, Matičič, Mojca, Ruta, Simona Maria, Rivero-Juárez, Antonio, van Welzen, Berend Joost, Tan, Boun Kim, Garcia, Federico, Gherlan, George Sebastian, Çınar, Güle, Hasanoğlu, İmran, Gmizić, Ivana, Nicolini, Laura Ambra, Santos, Lurdes, Sargsyants, Narina, Velikov, Petar, Habibović, Selma, Fourati, Slim, Židovec-Lepej, Snježana, Herder, Vanessa, Dudman, Susanne, Miron, Victor Daniel, Irving, William, Şahin, Gülşen Özkaya
Format: Article
Language:English
Subjects:
adeno-associated virus
adenovirus
epidemiology
hepatitis
outbreak
paediatric
Pharmacology
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Summary:During the first half of 2022, the World Health Organization reported an outbreak of acute severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from the United Kingdom (UK) where a cluster of cases was first observed in previously well children aged
ISSN:1663-9812
1663-9812
DOI:10.3389/fphar.2022.1062408