Longitudinal changes in optic disc cupping from the baseline in chiasmal lesion optic neuropathy and glaucoma

We aimed to investigate the changes in cupping in chiasmal lesion optic neuropathy (chON) compared to baseline optic disc and glaucoma. We used a novel study design to enroll patients who had fundus photographs incidentally taken during routine health check-ups prior to the onset of optic neuropathy...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2024-04, Vol.14 (1), p.8889-8889, Article 8889
Main Authors: Lee, Eun Jung, Han, Jong Chul, Kang, Mira, Kong, Doo-Sik, Hong, Sang Duk, Park, Kyung-Ah, Kee, Changwon
Format: Article
Language:English
Subjects:
692/699
692/699/3161
692/699/3161/3172
Differential diagnosis
Eye
Glaucoma
Humanities and Social Sciences
Lesions
multidisciplinary
Optic neuropathy
Science
Science (multidisciplinary)
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We aimed to investigate the changes in cupping in chiasmal lesion optic neuropathy (chON) compared to baseline optic disc and glaucoma. We used a novel study design to enroll patients who had fundus photographs incidentally taken during routine health check-ups prior to the onset of optic neuropathy. In 31 eyes (21 patients) with chON and 33 eyes (30 patients) with glaucoma, we investigated the change in cup-to-disc (C/D) area from the baseline to overt cupping using flicker analysis. Compared to the baseline, 23 eyes (74.2%) had increased cup size and 3 (9.7%) had vascular configuration changes in the chONgroup; in contrast, all glaucoma eyes exhibited changes in cup size and vascular configuration. The increase in C/D area ratio was significantly smaller in chON (0.04 ± 0.04) compared to glaucoma (0.10 ± 0.04, P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-59419-3