Retention of testicular integrity and testosterone levels upon ingestion of garlic cloves(Allium sativum)in the Sprague-Dawley rat

Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels.Methods: Twenty(20) male Sprague-Dawley rats weighing an average of 120 g were used.Animals were divided into three groups. Group A served as con...

Full description

Saved in:
Bibliographic Details
Published in:Asian Pacific journal of tropical biomedicine 2015-04, Vol.5 (4), p.319-323
Main Authors: Memudu, Adejoke Elizabeth, Akinrinade, Ibukun Dorcas, Ogundele, Olalekan Michael
Format: Article
Language:English
Subjects:
Allium
Allium sativum
sativum
Testis
Testosterone
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: To investigate the effects of acute and chronic aqueous garlic extract ingestion on testicular cellular integrity and serum testosterone levels.Methods: Twenty(20) male Sprague-Dawley rats weighing an average of 120 g were used.Animals were divided into three groups. Group A served as control(10 rats for 28 and 56 d respectively), while treatment Groups B and C were given 200 mg/kg for Allium sativum(garlic cloves) extract for 28 and 56 d respectively.Results: Histological analysis revealed the presence of all spermatogenic lineages, appearance of proliferative activities in the interstitial cells, as well as increased serum testosterone levels.Conclusions: This study confirmed proliferative and restorative potentials in both acute and chronic garlic ingestion.
ISSN:2221-1691
2588-9222
DOI:10.1016/S2221-1691(15)30351-8