Marine Microbial Diversity as a Source of Bioactive Natural Products

Genetic drift and natural selection have molded the phenotypic expression of a trillion different microbial species [1], shaping their metabolisms and offering ever-more advantageous abilities to expand, with the production of new metabolites being one key to the fitness and evolutionary success of...

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Bibliographic Details
Published in:Marine drugs 2020-04, Vol.18 (4), p.215
Main Author: Stien, Didier
Format: Article
Language:English
Subjects:
Animals
Aquatic Organisms - chemistry
Biological activity
Biological Products - isolation & purification
Chemical analysis
Chemical Sciences
DNA
Fungi
Fungi - chemistry
Genetic analysis
Genetic drift
Marine environment
Metabolism
Metabolites
Microorganisms
n/a
Natural products
Natural selection
New species
Offshore structures
Other
Phylogenetics
Products
Purification
Water purification
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Summary:Genetic drift and natural selection have molded the phenotypic expression of a trillion different microbial species [1], shaping their metabolisms and offering ever-more advantageous abilities to expand, with the production of new metabolites being one key to the fitness and evolutionary success of new species [2]. The rate of discovery of new natural products of microbial origin has increased significantly since the 1970s with the advent of modern methods of purification and structural determination, and later, with holistic approaches to chemical analysis and genetic information-based exploration of natural chemodiversity [3,4,5,6]. The Special Issue “Marine Microbial Diversity as a Source of Bioactive Natural Products” was aimed at collecting papers with up-to-date information regarding the characterization of marine microbes’ metabolic diversity and the evaluation of the therapeutic potential of marine microbes’ metabolites. [...]not all fungi detected in marine environments by rDNA-based analysis are genuine marine species.
ISSN:1660-3397
1660-3397
DOI:10.3390/md18040215