The predominance of seafood allergy in Vietnamese adults: Results from the first population-based questionnaire survey

• Published in: The World Allergy Organization journal 2020-03, Vol.13 (3), p.100102, Article 100102
• Main Authors: Le, Thu T.K., Tran, Thuy T.B., Ho, Huong T.M., Vu, An T.L., McBryde, Emma, Lopata, Andreas L.
• Format: Article
• Language: English
• Subjects: Adults; Allergens; Allergies; Anaphylaxis; Colleges & universities; Crustaceans; Food allergies; Food allergy; Population; Prevalence; Questionnaires; Response rates; Seafood; Seafood allergy; Self report; Vietnam
• ISSN: 1939-4551; 1939-4551
• DOI: 10.1016/j.waojou.2020.100102

Food allergy (FA) is a serious, costly and growing health problem worldwide. FA occurs in both children and adults; however, there is a paucity of information on FA prevalence and its clinical features in the adult population, especially in Asia. We sought to assess the prevalence of FAs in Vietnamese adults and the distribution of offending food items among different regions throughout Vietnam. A nationwide, cross-sectional, population-based survey was conducted among University students aged 16–50 years. We used a structured, anonymous questionnaire, which was modified from recently published FA epidemiologic studies and based on European Academy of Allergy and Clinical Immunology (EAACI) guidelines, to collect data on FA prevalence, clinical presentations, and implicated food groups. Statistical analysis was performed to generate the prevalence of self-reported and doctor-diagnosed FA and to examine the association of key environmental factors and FA incidence in this population. Of the 14,500 surveys distributed, a total of 9,039 responses were returned, resulting in a response rate of 62.4%. Among participants who reported food-induced adverse reactions, 48.0% have repeated reactions. 18.0% of the participants perceived FA symptoms, but less than half of them sought medical services for confirmation (37.9%). Stratifying for true FA symptoms, the prevalence of self-reported FA was 11.8% and of doctor-diagnosed FA, 4.6%. The most common doctor-diagnosed FA was to crustacean (3.0%; 95% CI, 2.6–3.3), followed by fish (1.6%; 95% CI, 1.3–1.8), mollusk (1.3%; 95% CI, 1.0–1.5) and beef (1.0%; 95% CI, 0.8–1.2). The prevalence of doctor-diagnosed FA differed among participants living in urban (6.5%) and rural regions (4.9%) (P