Accelerated partial breast irradiation with interstitial multicatheter brachytherapy after breast-conserving surgery for low-risk early breast cancer

Patients with low-risk invasive ductal carcinoma treated with breast-conserving surgery (BCS) were included in a multicatheter brachytherapy APBI protocol. The primary endpoint was ipsilateral breast recurrence. Between December 2008–December 2017, 186 low-risk breast cancer patients were treated wi...

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Bibliographic Details
Published in:Breast (Edinburgh) 2020-08, Vol.52, p.45-49
Main Authors: Rodriguez-Ibarria, Nieves G., Pinar, Ma Beatriz, García, Laura, Cabezón, M. Auxiliadora, Lloret, Marta, Rey-Baltar, Ma Dolores, Rdguez-Melcón, J. Ignacio, Lara, Pedro C.
Format: Article
Language:English
Subjects:
Aged
Brachytherapy
Brachytherapy - methods
Breast cancer
Breast Neoplasms - radiotherapy
Carcinoma, Ductal, Breast - radiotherapy
Early breast cancer
Early Detection of Cancer
Female
Humans
Middle Aged
Neoplasm Recurrence, Local - radiotherapy
Partial breast irradiation
Radiotherapy Dosage
Short Communication
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Summary:Patients with low-risk invasive ductal carcinoma treated with breast-conserving surgery (BCS) were included in a multicatheter brachytherapy APBI protocol. The primary endpoint was ipsilateral breast recurrence. Between December 2008–December 2017, 186 low-risk breast cancer patients were treated with APBI using interstitial multicatheter brachytherapy and followed prospectively. At 5-years of follow-up, cumulative local recurrence (LR) and cause-specific survival was 1.1% (95% CI 0.3–1.9) and 98.3% (95% CI 97.3–99.3%) respectively. No grade 3 adverse effects were observed. Postoperative APBI using multicatheter brachytherapy after BCS in early breast cancer patients have excellent rates of local control and survival, without significant toxicity. •Low risk early breast cancer patients have low rate of recurrences.•APBI with interstitial multicatheter brachytherapy in low risk early breast cancer patients have excellent rates of local control and survival.•Reducing time of treatment.•Reducing adverse effects.
ISSN:0960-9776
1532-3080
DOI:10.1016/j.breast.2020.04.008