Left ventricular geometry transition in hypertensive patients with heart failure with preserved ejection fraction

Aims Heart failure with preserved ejection fraction (HFpEF) develops in response to hypertensive left ventricular (LV) hypertrophy and is associated with increased cardiovascular events. Although the progression to systolic heart failure is a known consequence of LV hypertrophy and HFpEF, few data a...

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Bibliographic Details
Published in:ESC Heart Failure 2021-08, Vol.8 (4), p.2784-2790
Main Authors: Guan, Ping, Gu, Jun, Song, Zhi‐ping, Wang, Chang‐qian, Hu, Wei, Zhang, Jun‐feng
Format: Article
Language:English
Subjects:
Beta blockers
Body mass index
Cardiomyopathy
Cardiovascular disease
Chronic obstructive pulmonary disease
Diabetes
Ejection fraction
Heart failure
Hypertension
Left ventricular hypertrophy
Medical prognosis
Mortality
Original
Original s
Patients
Peptides
Statistical analysis
Transition
Variables
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Summary:Aims Heart failure with preserved ejection fraction (HFpEF) develops in response to hypertensive left ventricular (LV) hypertrophy and is associated with increased cardiovascular events. Although the progression to systolic heart failure is a known consequence of LV hypertrophy and HFpEF, few data are available on the LV geometry change and frequency of deterioration to systolic dysfunction in this population. Methods and results We evaluated the baseline and follow‐up characteristics in 680 patients with LV hypertrophy and HFpEF in this prospective cohort study. The primary endpoint was 5 year all‐cause mortality. The changes of LV geometry and heart failure transition were analysed. Systolic dysfunction [left ventricular ejection fraction (LVEF) 
ISSN:2055-5822
2055-5822
DOI:10.1002/ehf2.13349