Effects of Vitamin D Supplementation on Surrogate Markers of Fertility in PCOS Women: A Randomized Controlled Trial

Vitamin D (VD) might play an important role in polycystic ovary syndrome (PCOS) and female fertility. However, evidence from randomized controlled trials (RCT) is sparse. We examined VD effects on anti-Müllerian hormone (AMH) and other endocrine markers in PCOS and non-PCOS women. This is a post hoc...

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Bibliographic Details
Published in:Nutrients 2021-02, Vol.13 (2), p.547
Main Authors: Lerchbaum, Elisabeth, Theiler-Schwetz, Verena, Kollmann, Martina, Wölfler, Monika, Pilz, Stefan, Obermayer-Pietsch, Barbara, Trummer, Christian
Format: Article
Language:English
Subjects:
17β-Estradiol
25-Hydroxyvitamin D
Alfacalcidol
Analysis
Androstenedione
anti-Müllerian hormone
Calcifediol
Calciferol
Confidence intervals
Dehydroepiandrosterone
Dehydroepiandrosterone sulfate
Drugs
Endocrinology
Enzymes
Estradiol
Fertility
Follicle-stimulating hormone
Glycoproteins
Health services
Insulin
Laboratories
Luteinizing hormone
Markers
Medical colleges
Metabolism
Obesity
Ovaries
Placebos
Polycystic ovary syndrome
randomized controlled trial
Sex hormones
Stein-Leventhal syndrome
Type 2 diabetes
Vitamin D
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Summary:Vitamin D (VD) might play an important role in polycystic ovary syndrome (PCOS) and female fertility. However, evidence from randomized controlled trials (RCT) is sparse. We examined VD effects on anti-Müllerian hormone (AMH) and other endocrine markers in PCOS and non-PCOS women. This is a post hoc analysis of a single-center, double-blind RCT conducted between December 2011 and October 2017 at the endocrine outpatient clinic at the Medical University of Graz, Austria. We included 180 PCOS women and 150 non-PCOS women with serum 25-hydroxyvitamin D (25(OH)D) concentrations
ISSN:2072-6643
2072-6643
DOI:10.3390/nu13020547