Assessment of the Correlation Between Serum Phosphate Level and Muscle Strength as Measured by Handgrip Strength in Patients Treated With Hemodialysis

Background: Sarcopenia, commonly observed in patients treated with hemodialysis, correlates with low serum phosphate levels. Although normophosphatemia is desired, dietary phosphate restriction is difficult to achieve and may result in undesirable protein restriction. Objective: We aimed to evaluate...

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Bibliographic Details
Published in:Canadian journal of kidney health and disease 2024-01, Vol.11, p.20543581241267163
Main Authors: Ben-Noach, Dror, Levy, Dina, Raz, Michal, Anbar, Ronit, Schwartz, Doron, Kliuk-Ben Bassat, Orit
Format: Article
Language:English
Subjects:
Creatinine
Diabetes
Hemodialysis
Mortality
Muscle strength
Original Clinical Research Quantitative
Proteins
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Summary:Background: Sarcopenia, commonly observed in patients treated with hemodialysis, correlates with low serum phosphate levels. Although normophosphatemia is desired, dietary phosphate restriction is difficult to achieve and may result in undesirable protein restriction. Objective: We aimed to evaluate whether hyperphosphatemia is associated with higher muscle strength in patients receiving hemodialysis treatment. Design: A single-center prospective observational study. Setting: Ambulatory prevalent patients undergoing hemodialysis treatments in a dialysis unit of a tertiary hospital. Patients: Participants included prevalent patients treated with hemodialysis. All patients were above 18 years. Only patients with residual kidney function below 200 mL/24 hours were included to avoid bias. Measurements: Muscle strength was measured by handgrip strength (HGS). Each patient repeated 3 measurements, and the highest value was recorded. Handgrip strength cutoffs for low muscle strength were defined as
ISSN:2054-3581
2054-3581
DOI:10.1177/20543581241267163