Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy

To report clinical outcomes of a patient with unilateral neurotrophic keratitis following penetrating keratoplasty for lattice dystrophy treated with topical recombinant human nerve growth factor. A 75-year-old male with lattice dystrophy and history of herpes simplex keratitis, presented with recur...

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Bibliographic Details
Published in:American journal of ophthalmology case reports 2021-06, Vol.22, p.101058, Article 101058
Main Authors: Gouvea, Larissa, Penatti, Raphael, Rocha, Karolinne Maia
Format: Article
Language:English
Subjects:
Case Report
Growth factor
Lattice dystrophy
Neurotrophic keratitis
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Summary:To report clinical outcomes of a patient with unilateral neurotrophic keratitis following penetrating keratoplasty for lattice dystrophy treated with topical recombinant human nerve growth factor. A 75-year-old male with lattice dystrophy and history of herpes simplex keratitis, presented with recurrent neurotrophic ulceration in the right eye two years following penetrating keratoplasty. The patient was successfully treated with topical recombinant human nerve growth factor. Neurotrophic keratitis is a rare chronic disorder that affects quality of life due to the risk of vision loss. Topical recombinant human nerve growth factor is a novel and effective treatment option that may help improve optical quality and patient's satisfaction as shown in this case of recurrent neurotrophic keratitis.
ISSN:2451-9936
2451-9936
DOI:10.1016/j.ajoc.2021.101058