Monitoring radiographic brain tumor progression

Determining radiographic progression in primary malignant brain tumors has posed a significant challenge to the neuroncology community. Glioblastoma multiforme (GBM, WHO Grade IV) through its inherent heterogeneous enhancement, growth patterns, and irregular nature has been difficult to assess for p...

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Bibliographic Details
Published in:Toxins 2011-03, Vol.3 (3), p.191-200
Main Authors: Mehta, Ankit I, Kanaly, Charles W, Friedman, Allan H, Bigner, Darell D, Sampson, John H
Format: Article
Language:English
Subjects:
Brain Neoplasms - diagnostic imaging
Brain tumors
Disease Progression
glioblastoma
Glioblastoma - diagnostic imaging
Humans
Magnetic Resonance Imaging - methods
MRI
Radiographic Image Enhancement
radiographic progression
Review
tumor progression
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Summary:Determining radiographic progression in primary malignant brain tumors has posed a significant challenge to the neuroncology community. Glioblastoma multiforme (GBM, WHO Grade IV) through its inherent heterogeneous enhancement, growth patterns, and irregular nature has been difficult to assess for progression. Our ability to detect tumor progression radiographically remains inadequate. Despite the advanced imaging techniques, detecting tumor progression continues to be a clinical challenge. Here we review the different criteria used to detect tumor progression, and highlight the inherent challenges with detection of progression.
ISSN:2072-6651
2072-6651
DOI:10.3390/toxins3030191