Early diagnosis strategy of calciphylaxis in dialysis patients

Calciphylaxis, a rapidly progressive and potentially life-threatening vascular calcification syndrome that clinically presents with persistently painful, ulcerative, or necrotizing skin lesions in multiple parts of the body, is predominantly observed in patients treated with dialysis. Early diagnosi...

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Bibliographic Details
Published in:Renal failure 2023, Vol.45 (2), p.2264407-2264407
Main Authors: Liu, Yuqiu, Zhang, Xiaoliang
Format: Article
Language:English
Subjects:
Anticoagulants
Biopsy
Body fat
Calcification
Calcification (ectopic)
Calciphylaxis
Diabetes
Diagnosis
Dialysis
Drug dosages
early diagnosis
Erythema
Hemodialysis
hierarchical diagnosis
Ischemia
Kidney diseases
Mortality
Nephrology
Pain
Proteins
Purpura
Review
Risk factors
Skin
skin biopsy
Skin diseases
Skin lesions
State-of-the-Art Review
Ulcers
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Description
Summary:Calciphylaxis, a rapidly progressive and potentially life-threatening vascular calcification syndrome that clinically presents with persistently painful, ulcerative, or necrotizing skin lesions in multiple parts of the body, is predominantly observed in patients treated with dialysis. Early diagnosis of calciphylaxis is a key measure for reducing high disability and mortality. At present, there is no unified diagnostic standard for calciphylaxis, and there is a lack of effective early screening strategies. This paper summarized and discussed the diagnostic accuracy of calciphylaxis based on the latest research worldwide. We propose a modified strategy for the early diagnosis of calciphylaxis, which is suitable for dialysis patients to help clinicians better identify such disease and improve prognosis.
ISSN:0886-022X
1525-6049
DOI:10.1080/0886022X.2023.2264407