Value of inversion imaging to diagnosis in differentiating malignant from benign breast masses

• Published in: BMC medical imaging 2023-12, Vol.23 (1), p.206-206, Article 206
• Main Authors: Li, Na, Hou, Zhongguang, Wang, Jiajia, Bi, Yu, Wu, Xiabi, Zhan, Yunyun, Peng, Mei
• Format: Article
• Language: English
• Subjects: Acoustics; Benign; Biopsy; Breast; Breast - diagnostic imaging; Breast - pathology; Breast cancer; Breast imaging reporting and Data System; Breast masses; Breast Neoplasms - diagnostic imaging; Breast Neoplasms - pathology; Breast Neoplasms - surgery; Data systems; Diagnosis; Diagnosis, Differential; Diagnostic systems; Female; Humans; Image processing; Inversion; Inversion imaging; Malignancy; Medical imaging; Methods; Neoplasms; Predictive Value of Tests; Sensitivity; Sensitivity and Specificity; Statistical analysis; Ultrasonography; Ultrasonography, Mammary - methods; Ultrasound
• ISSN: 1471-2342; 1471-2342
• DOI: 10.1186/s12880-023-01164-6

We aimed to evaluate the added value of inversion imaging in differentiating between benign and malignant breast masses when combined with the Breast Imaging Reporting and Data System (BI-RADS). A total of 364 patients with 367 breast masses (151 benign and 216 malignant) who underwent conventional ultrasound and inversion imaging prior to breast surgery were included. A 5-point inversion score (IS) scale was proposed based on the masses' internal echogenicity and distribution characteristics in the inversion images. The combination of IS and BI-RADS was compared with BI-RADS alone to evaluate the value of inversion imaging for breast mass diagnosis. The diagnostic performance of the BI-RADS and its combination with IS for breast masses were analyzed using area under the receiver operating characteristic curve (AUC), accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). The IS for malignant breast masses (3.96 ± 0.77) was significantly higher than benign masses (2.58 ± 0.98) (P