Changes in the lipidome of water buffalo milk during intramammary infection by non-aureus Staphylococci

This study aimed to determine the lipidome of water buffalo milk with intramammary infection (IMI) by non-aureus staphylococci (NAS), also defined as coagulase-negative staphylococci, using an untargeted lipidomic approach. Non-aureus Staphylococci are the most frequently isolated pathogens from dai...

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Bibliographic Details
Published in:Scientific reports 2022-06, Vol.12 (1), p.9665-9665, Article 9665
Main Authors: Ceciliani, Fabrizio, Audano, Matteo, Addis, Maria Filippa, Mitro, Nico, Lecchi, Cristina, Ghaffari, Morteza H., Albertini, Mariangela, De Carlo, Esterina, Vecchio, Domenico, Di Vuolo, Gabriele, Cappelli, Giovanna, Tangorra, Francesco, Piccinini, Renata, Bronzo, Valerio, Caruso, Donatella
Format: Article
Language:English
Subjects:
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Animals
Bubalus bubalis
Buffalo milk
Buffaloes
Cattle
Chromatography
Coagulase
Discriminant analysis
Fatty acids
Female
Humanities and Social Sciences
Infections
Lipidomics
Lipids
Liquid chromatography
Mammary Glands, Animal
Mass spectrometry
Mass spectroscopy
Mastitis
Mastitis, Bovine
Milk
multidisciplinary
Pathogens
Science
Science (multidisciplinary)
Scientific imaging
Staphylococcal Infections - veterinary
Staphylococcus
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Summary:This study aimed to determine the lipidome of water buffalo milk with intramammary infection (IMI) by non-aureus staphylococci (NAS), also defined as coagulase-negative staphylococci, using an untargeted lipidomic approach. Non-aureus Staphylococci are the most frequently isolated pathogens from dairy water buffalo milk during mastitis. A total of 17 milk samples from quarters affected by NAS-IMI were collected, and the lipidome was determined by liquid chromatography-quadrupole time-of-flight mass spectrometry. The results were compared with the lipidome determined on samples collected from 16 healthy quarters. The study identified 1934 different lipids, which were classified into 15 classes. The abundance of 72 lipids changed in NAS-IMI milk compared to healthy quarters. Significant changes occurred primarily in the class of free fatty acids. The results of this study provided first-time insight into the lipidome of dairy water buffalo milk. Moreover, the present findings provide evidence that NAS-IMI induces changes in water buffalo milk's lipidome.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-13400-0