Synthesis of angiotensin-converting enzyme (ACE) inhibitors: an important class of antihypertensive drugs

This report outlines the discovery, the design and development of new compounds, and, structure-activity relationships for this drug category. Updated approaches to planned syntheses of new worthy ACE-inhibitors are also exploited.

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Bibliographic Details
Published in:Química Nova 1999-06, Vol.22 (3), p.375-381
Main Author: Lima, Dênis Pires de
Format: Article
Language:English
Subjects:
ACE inhibitors
angiotensin
antihypertensive
CHEMISTRY, MULTIDISCIPLINARY
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Description
Summary:This report outlines the discovery, the design and development of new compounds, and, structure-activity relationships for this drug category. Updated approaches to planned syntheses of new worthy ACE-inhibitors are also exploited.
ISSN:0100-4042
1678-7064
0100-4042
1678-7064
DOI:10.1590/S0100-40421999000300016