Preterm Gut Microbiome Depending on Feeding Type: Significance of Donor Human Milk

Preterm microbial colonization is affected by gestational age, antibiotic treatment, type of birth, but also by type of feeding. Breast milk has been acknowledged as the gold standard for human nutrition. In preterm infants breast milk has been associated with improved growth and cognitive developme...

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Bibliographic Details
Published in:Frontiers in microbiology 2018-06, Vol.9, p.1376-1376
Main Authors: Parra-Llorca, Anna, Gormaz, María, Alcántara, Cristina, Cernada, María, Nuñez-Ramiro, Antonio, Vento, Máximo, Collado, Maria C
Format: Article
Language:English
Subjects:
donor human milk
formula milk
intestinal colonization
Microbiology
microbiota
preterm infant
their mother’s own milk
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Summary:Preterm microbial colonization is affected by gestational age, antibiotic treatment, type of birth, but also by type of feeding. Breast milk has been acknowledged as the gold standard for human nutrition. In preterm infants breast milk has been associated with improved growth and cognitive development and a reduced risk of necrotizing enterocolitis and late onset sepsis. In the absence of their mother's own milk (MOM), pasteurized donor human milk (DHM) could be the best available alternative due to its similarity to the former. However, little is known about the effect of DHM upon preterm microbiota and potential biological implications. Our objective was to determine the impact of DHM upon preterm gut microbiota admitted in a referral neonatal intensive care unit (NICU). A prospective observational cohort study in NICU of 69 neonates
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2018.01376