A review of botanical interventions for neuropathy and neuropathic pain

Neuropathy is a complex condition characterized by nerve damage and a wide range of symptoms, creating significant challenges in clinical management. Traditional pharmacological treatments often present partial efficacy and adverse side effects, prompting increasing interest in botanical interventio...

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Bibliographic Details
Published in:Clinical phytoscience 2024-12, Vol.10 (1), p.23-10, Article 23
Main Authors: Olalekan, Samuel Oluwadare, Okwute, Patrick Godwin, Osonuga, Ifabunmi Oduyemi, Adeyanju, Muinat Moronke
Format: Article
Language:English
Subjects:
Anagelsic
Analgesics
Anti-inflammatory
Antioxidant
Botanical interventions
Cannabis
Chronic pain
Diabetes
Diabetic neuropathy
Dosage
Drug therapy
Effectiveness
Gastroenterology
Gynecology
Long-term effects
Medicine
Medicine & Public Health
Neuropathic pain
Neuropathy
Pain
Pathophysiology
Pediatrics
Pharmacology
Physiology
Pneumology/Respiratory System
Quality of life
Review
Saffron
Side effects
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Description
Summary:Neuropathy is a complex condition characterized by nerve damage and a wide range of symptoms, creating significant challenges in clinical management. Traditional pharmacological treatments often present partial efficacy and adverse side effects, prompting increasing interest in botanical interventions. This review evaluates the effectiveness of various plants in treating neuropathy and neuropathic pain, focusing on their pharmacological properties, mechanisms of action, clinical studies, dosage, and safety profiles. Notable plants include Crocus sativus (saffron), Citrullus colocynthis (bitter apple), Curcuma longa (turmeric), Lavandula angustifolia (lavender), and Cannabis sativa. These botanicals demonstrate anti-inflammatory, antioxidative, and analgesic effects, highlighting their potential to reduce neuropathic pain and improve patients’ quality of life. Future research should focus on optimizing dosages, clarifying long-term effects, and integrating botanicals into broader treatment protocols for neuropathic care.
ISSN:2199-1197
2199-1197
DOI:10.1186/s40816-024-00385-8