Giant Intracranial Xanthoma with Cloudy Vision as the First Symptom: A Case Report and Literature Review

A 31-year-old male with mild dizziness complained of cloudy vision in his right eye for 5 days. The visual acuity of both eyes was normal, while the visual contrast sensitivity of both eyes slightly reduced. Fundus examination showed the swollen and radial superficial hemorrhage of his both optic ne...

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Bibliographic Details
Published in:International journal of general medicine 2021-01, Vol.14, p.1101-1105
Main Authors: Wang, Xueting, Li, Xuejiao, Liu, XuHui, Yin, Yizhe, Dang, Yalong, Lei, Fang
Format: Article
Language:English
Subjects:
Blood
Case Report
Case reports
Cholesterol
Disease
Edema
Hemorrhage
Histology
intracranial xanthoma
Lipids
Lipoproteins
Medical examination
Nervous system diseases
neurological disorder
optic disc edema
optic nerve
visual function
Citations: Items that this one cites
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Summary:A 31-year-old male with mild dizziness complained of cloudy vision in his right eye for 5 days. The visual acuity of both eyes was normal, while the visual contrast sensitivity of both eyes slightly reduced. Fundus examination showed the swollen and radial superficial hemorrhage of his both optic nerves. Brain MRI scan indicated a huge tumor in the right temporal lobe with clear boundary, close to the skull. The midline structure shifted to the left. Blood tests indicated no hyperlipidemia or lipid disorders. The patient then received tumor resection. The size of the tumor was 5.6 cm × 7.5 cm × 10.1 cm. Histology suggested many foam cell accumulations and the tumor was positive for CD34, CD99, Vimentin, β-Catenin and CD68, but negative for EMA, GFAP, IDH-1, Oliga-2, PR, S-100, and CD1a. Three months after surgery, MRI showed the midline structure was back to normal. The swollen and radial superficial hemorrhage of optic nerves had disappeared. The visual acuity and visual field remained normal.
ISSN:1178-7074
1178-7074
DOI:10.2147/IJGM.S290893