Multifunctional Profiling of Moringa oleifera Leaf Extracts for Topical Application: A Comparative Study of Different Collection Time

This research investigated plant extracts as a source of potential new actives in the nutritional, cosmetic, and pharmaceutical fields. which is extensively known for its nutritional properties, has been investigated in this work by preparation, characterization, and evaluation of the antioxidant (F...

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Bibliographic Details
Published in:Antioxidants 2023-02, Vol.12 (2), p.411
Main Authors: Baldisserotto, Anna, Barbari, Riccardo, Tupini, Chiara, Buzzi, Raissa, Durini, Elisa, Lampronti, Ilaria, Manfredini, Stefano, Baldini, Erika, Vertuani, Silvia
Format: Article
Language:English
Subjects:
Acids
Altitude
Antioxidants
butyl methoxydibenzoylmethane
Cytotoxicity
Environmental conditions
Erythema
extracts
Flavonoids
Investigations
Melanoma
Moringa oleifera
Moringa oleifera leaves
natural antioxidants
Oxidative stress
Photodegradation
photostability
Plant extracts
Polyphenols
Skin cancer
Sunscreens
Topical application
Ultraviolet radiation
UV filter
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Summary:This research investigated plant extracts as a source of potential new actives in the nutritional, cosmetic, and pharmaceutical fields. which is extensively known for its nutritional properties, has been investigated in this work by preparation, characterization, and evaluation of the antioxidant (FRAP, DPPH, ORAC, and PCL test), antifungal, photoprotective, and cytotoxicity profile against human melanoma Colo38 cell line of two different extracts (hydroalcoholic and methanolic) and one infusion of dry leaves collected from Paraguay in four distinct harvest times (February, March, April, and May 2017). The outcomes of this study highlight as a potential ally to counteract skin aging and oxidative stress, as indicated by the favorable antioxidant profile of the extracts and infusions of Paraguay, which was, in all cases, superior to that provided by the same plant species when collected from Senegal. Moreover, some samples were more efficient in preventing the photodegradation of UVA filter butyl methoxydibenzoylmethane (Avobenzone) compared to commercial filters, thus suggesting an interesting future role as natural additives in sunscreens.
ISSN:2076-3921
2076-3921
DOI:10.3390/antiox12020411