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Association of term isolated microcephaly with mode of delivery and perinatal outcome - a retrospective case-control analysis

We aimed to evaluate the association of isolated fetal microcephaly measured by ultrasound prior to delivery at term with mode of delivery and perinatal outcome. A single-center retrospective study was conducted in 2012-2016. Fetal microcephaly was defined as head circumference > 2 standard devia...

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Published in:BMC pregnancy and childbirth 2021-02, Vol.21 (1), p.115-115, Article 115
Main Authors: Bardin, Ron, Krispin, Eyal, Salman, Lina, Navon, Inbal, Shmueli, Anat, Perlman, Sharon, Gilboa, Yinon, Hadar, Eran
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Language:English
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Summary:We aimed to evaluate the association of isolated fetal microcephaly measured by ultrasound prior to delivery at term with mode of delivery and perinatal outcome. A single-center retrospective study was conducted in 2012-2016. Fetal microcephaly was defined as head circumference > 2 standard deviations of the mean for gestational age and sex. We compared the obstetric, delivery, and outcome parameters of women in whom ultrasound performed up to 10 days prior to term delivery showed isolated fetal microcephaly (study group) or normal head circumference (reference group). Exclusion criteria were intrauterine fetal death, birthweight below the 10th percentile, and antepartum cesarean delivery for any indication. Of 3677 women included in the study, 26 (0.7%) had a late ultrasound finding of isolated fetal microcephaly. Baseline characteristics were similar in the two groups except for estimated fetal weight based on abdominal circumference and biparietal diameter, which was lower in the microcephaly group (3209.8 ± 557.6 vs. 2685.8 ± 420.8 g, p 
ISSN:1471-2393
1471-2393
DOI:10.1186/s12884-021-03613-y