EFFECT OF ENDURANCE EXERCISE ON BRAIN NATRIURETIC PEPTIDE

OBJECTIVE: To evaluate the effect of maximal exercise on the level ofbrain natriuretic peptide (BNP) and cardiac adaptive changes in endurancetrained elite athletes and sedentary healthy subjects. METHODOLOGY: This Cross-sectional comparative study was conductedat Army Medical College in collaborati...

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Bibliographic Details
Published in:Khyber Medical University journal 2013-06, Vol.5 (2)
Main Authors: Ali, Hafeezullah Wazir, Aslam, Muhammad, MazharHussein, Muhammad, Aziz, Sohail, Wazir, Farmanullah
Format: Article
Language:English
Subjects:
Athletes
Brain natriuretic peptide
Cardiovascular system
Exercise
Health aspects
Physiological aspects
Sedentary behavior
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Summary:OBJECTIVE: To evaluate the effect of maximal exercise on the level ofbrain natriuretic peptide (BNP) and cardiac adaptive changes in endurancetrained elite athletes and sedentary healthy subjects. METHODOLOGY: This Cross-sectional comparative study was conductedat Army Medical College in collaboration with Armed ForcesInstitute of Cardiology (AFIC) Rawalpindi. Twenty two elite enduranceathletes (Long Distance Runners) and 22 matching sedentary (from sameunit having no sports activity) controls were selected by convenience(non-probability) sampling technique. Height, body weight, blood pressure,pulse rate and ECG were recorded. The blood was drawn fromantecubital vein for measuring BNP and aldosterone before exerciseand again after exercise. The echocardiography of left ventricle wasdone to measure the end-diastolic internal diameter (LVIDd), diastolicinterventricular septal thickness (IVSTd), and diastolic posterior wallthickness (PWTd). The left ventricular mass (LVM) was calculated byDevereux formula. The data were recorded in a proforma and analyzedby SPSS version 10. RESULTS: It was observed that the heart rate and blood pressure ofathletes were significantly less than the controls (p
ISSN:2305-2643
2305-2651