Seroepidemiology of hepatitis A virus in Hyderabad, South India

The present study was carried to determine the prevalence of He-patitis A virus (HAV) IgM antibody among general population in Hyderabad since January 2002 to December 2011. A total of 4571 subjects were selected and divided into groups on the basis of age. The serum samples were screened for the pr...

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Bibliographic Details
Published in:Journal of medical and allied sciences 2012-08, Vol.2 (2), p.58-61
Main Authors: Syed, Rahamathulla, Mohammed, Aejaz Habeeb, Sindiri, Prathap Kumar, Nathani, Arif Aziz, Rao, Ramachandra V V, Satti, Vishnu Priya, Chandra, Madhavi, Khaja, Mahammad Nanne
Format: Article
Language:English
Subjects:
Age
ELISA
Epidemiology
HAV
Hepatitis
Males
Mortality
Public health
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Summary:The present study was carried to determine the prevalence of He-patitis A virus (HAV) IgM antibody among general population in Hyderabad since January 2002 to December 2011. A total of 4571 subjects were selected and divided into groups on the basis of age. The serum samples were screened for the presence of HAV IgM antibodies (anti-HAV IgM) using a commercially availa-ble enzyme linked immunosorbent assay (ELISA) kit. Of the 4571 serum samples, 4257 were negative and 314 (6.87%) were posi-tive for the HAV IgM assay. The disease predominance was more in males (212) with 67.51% compared to females (102) with 32.48%. Anti-HAV seroprevalence was measured for the following age groups: Early (≤20 years), Middle (21-40 years) and Late (≥41 years). Average age-wise IgM-anti-HAV positivity from 2002-2011 was 234 of 314 in ≤20 years, 74.52%), 73 of 314 (21-40 years, 23.24%), and 7 of 314 (≥41 years, 2.22%). The present study will provide insights to the recent epidemiologic features of HAV infec-tion in South India. [PUBLICATION ABSTRACT]
ISSN:2231-1696
2231-170X