Cryopreserved valved femoral vein homografts for right ventricular outflow tract reconstruction in infantsCentral MessagePerspective

Background: We have previously reported use of cryopreserved valve femoral vein homograft (FVH) conduits for biventricular repairs in infants needing right ventricular outflow tract (RVOT) reconstruction. This study aims to compare FVH conduits with aortic (A) and pulmonary (P) homografts with regar...

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Bibliographic Details
Published in:JTCVS open 2020-12, Vol.4, p.58-65
Main Authors: Lok Sinha, MD, Lucas Mota, BS, Mahmut Ozturk, MD, Steven J. Staffa, MS, David Zurakowski, MS, PhD, Richard A. Jonas, MD, Pranava Sinha, MD
Format: Article
Language:English
Subjects:
CHD—valve lesions
homograft
pulmonary valve
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Summary:Background: We have previously reported use of cryopreserved valve femoral vein homograft (FVH) conduits for biventricular repairs in infants needing right ventricular outflow tract (RVOT) reconstruction. This study aims to compare FVH conduits with aortic (A) and pulmonary (P) homografts with regards to intermediate- and long-term outcomes. Methods: Retrospective review was conducted of all infants between 2004 and 2016 who underwent biventricular repair with RVOT reconstruction using homograft conduits. Patients were divided into A, P, and FVH groups based upon type of conduit received (N = 57 [A = 13; P = 21, FVH = 23]). Groups were compared using univariate and multivariable Cox regression analyses. The Nelson–Aalen estimator of cumulative hazard and Kaplan–Meier curves were used to identify differences in freedom from catheter reintervention and reoperation. Results: The 2 groups were comparable except for greater incidence of delayed sternal closure and longer hospital length of stay in the FVH group. The follow-up was longer for A and P groups compared with the FVH group (P 
ISSN:2666-2736
2666-2736