The fight against gram-negative superbugs in the intensive care units

To determine the factors affecting mortality in patients with gram-negative bloodstream infections (GNBSI) in intensive care units (ICU). Mortality and morbidity from GNBSI are high due to the increasing antimicrobial resistance of gram-negative patogens and the limited access to available antibioti...

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Bibliographic Details
Published in:Journal of global antimicrobial resistance. 2024-12, Vol.39, p.48-48
Main Authors: Sezer, Beyza, Ayaz, Caglayan Merve, Yildiz, Ulku Arslan, Yalcin, Ata Nevzat
Format: Article
Language:English
Subjects:
bloodstream infections
Gram negative bacteria
mortality
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Summary:To determine the factors affecting mortality in patients with gram-negative bloodstream infections (GNBSI) in intensive care units (ICU). Mortality and morbidity from GNBSI are high due to the increasing antimicrobial resistance of gram-negative patogens and the limited access to available antibiotics. A comprehensive understanding of the associated factors is therefore essential to reduce mortality. The study was conducted retrospectively in Akdeniz University Hospital, Turkiye, between January 2020 and December 2022. Data from 202 patients with GNBSI in the ICU were analysed. Of the patients 65.8% were male. Of the patients 70.7% died. Mortality rates were lower in ICU admissions due to neurological disease and trauma (p=0.001), in those who had a tracheostomy (p=0,001) and were fed with a percutaneous endoscopic gastrostomy (p=0,025). Mortality rates were higher in patients in isolated rooms (p=0.003). The analysis indicated that older age (p=0.01), concomitant pulmonary diseases (p
ISSN:2213-7165
DOI:10.1016/j.jgar.2024.10.153