Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update

Febrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival. This paper reviews the guidelines about febrile neutropenia in the setting of hemato...

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Bibliographic Details
Published in:Advances in hematology 2014, Vol.2014 (2014), p.1-9
Main Authors: Henriquez-Camacho, Cesar, Losa, Juan, Villalon, Lucia, Villafuerte-Gutierrez, Paola
Format: Article
Language:English
Subjects:
Antibiotics
Bacteria
Bacterial infections
Blood cancer
Cancer therapies
Chemotherapy
Chronic obstructive pulmonary disease
Comorbidity
Drug resistance
Fever
Fungal infections
Hematology
Hypotension
Mortality
Neutropenia
Neutrophils
Pathogens
Patients
Review
Risk assessment
Staphylococcus infections
Streptococcus infections
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Summary:Febrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival. This paper reviews the guidelines about febrile neutropenia in the setting of hematologic malignancies, providing an overview of the definition of fever and neutropenia, and categories of risk assessment, management of infections, and prophylaxis.
ISSN:1687-9104
1687-9112
DOI:10.1155/2014/986938