Congenital and Blood Transfusion Transmission of Chagas Disease: A Framework Using Mathematical Modeling

Chagas disease or American trypanosomiasis is an important health problem in Latin America. Due to the mobility of Latin American population around the world, countries without vector presence started to report disease cases. We developed a deterministic compartmental model in order to gain insights...

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Bibliographic Details
Published in:Complexity (New York, N.Y.) N.Y.), 2018-01, Vol.2018 (2018), p.1-10
Main Authors: López, Daniel, Gómez i Prat, Jordi, Lorena, Virginia, Cristino, Cláudio, Albuquerque, Jones, Ramalho, Edneide, Prats, Clara
Format: Article
Language:English
Subjects:
Analysis
Blood & organ donations
Blood transfusion
Blood transfusions
Chagas' disease
Chagas, Malaltia de
Congenital diseases
Demographics
Epidemiology
Health care
Infections
Investigació operativa
Matemàtiques i estadística
Mathematical models
Mortality
Parameter sensitivity
Parasites
Sensitivity analysis
Simulació
Surveillance
Systematic review
Transfusió de sang
Transplantation of organs, tissues, etc
Tropical diseases
Womens health
Àrees temàtiques de la UPC
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Summary:Chagas disease or American trypanosomiasis is an important health problem in Latin America. Due to the mobility of Latin American population around the world, countries without vector presence started to report disease cases. We developed a deterministic compartmental model in order to gain insights into the disease dynamics in a scenario without vector presence, considering congenital transmission and transmission by blood transfusion. The model was used to evaluate the epidemiological effect of control measures. It was applied to demographic data from Spain and sensitivity analysis was performed on model parameters associated with control strategies.
ISSN:1076-2787
1099-0526
DOI:10.1155/2018/1589016