An Efficient Synthesis of Acenaphtho[1,2- b ]indole Derivatives via Domino Reaction

A concise and efficient synthesis of acenaphtho[1,2- ]indole derivatives via the domino reactions of enaminones with acenaphthoquinone catalyzed by l-proline has been developed. This protocol has the advantages of good yields, operational convenience and high regioselectivity.

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2018-11, Vol.23 (11), p.3045
Main Authors: Zhang, Guo-Ning, Yuan, Xia, Niu, Weiping, Zhu, Mei, Wang, Juxian, Wang, Yucheng
Format: Article
Language:English
Subjects:
acenaphtho[1,2-b]indole
acenaphthoquinone
Acids
Cascade chemical reactions
Chemical reactions
domino reaction
Efficiency
enaminone
Indoles
L-Proline
Proline
Regioselectivity
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Description
Summary:A concise and efficient synthesis of acenaphtho[1,2- ]indole derivatives via the domino reactions of enaminones with acenaphthoquinone catalyzed by l-proline has been developed. This protocol has the advantages of good yields, operational convenience and high regioselectivity.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules23113045