A STUDY OF PULMONARY FUNCTION TEST IN TYPE 2 DIABETES MELLITUS

Introduction: Type 2 Diabetes mellitus is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. These processes play the main role in causing impairments of collagen & elastin cross linkage, which thereby causes red...

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Bibliographic Details
Published in:National journal of medical research 2021-03, Vol.11 (1)
Main Authors: Harmesh A Patel, Yash K Rajan, Ankur S Patel, Piyush Patoliya
Format: Article
Language:English
Subjects:
BMI
Body mass index
Gycosylated hemoglobin
HbA1C
PFT
Pulmonary function test
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Summary:Introduction: Type 2 Diabetes mellitus is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. These processes play the main role in causing impairments of collagen & elastin cross linkage, which thereby causes reduced elasticity of connective tissue. .The presence of abundant connective tissue and micro-vascular circulation in lung raises the possibility that in diabetic patients, lung could also be a “target organ”.Pulmonary function test is a useful test to assess involvement of lung connective tissues and micro vascular bed in diabetic patients. Methods: In this study, which was conducted in a tertiary care hospital of South Gujarat, we enrolled 65 subjects who were known cases diabetes mellitus. Result: Diabetes Mellitus in patients alters Various parameters of PFT like FVC, FEV1 which are reduced while FEV1/FVC increased showed restrictive pattern compared to normal individual. Conclusion: Diabetes mellitus patients have positive correlation with interpretation of PFT as with HbA1c increases a greater number of patients develop abnormal PFT in which Restrictive pattern is seen more commonly.
ISSN:2249-4995
2277-8810