New Delhi. Metallo-beta-lactamase in Klebsiella pneumoniae and Escherichia coli, Canada

Multidrug-resistant Klebsiella pneumoniae and Escherichia coli isolates harboring New Delhi metallo-β-lactamase (NDM-1) were isolated from a patient who had returned to Canada from India. The NDM-1 gene was found on closely related incompatibility group A/C type plasmids. The occurrence of NDM-1 in...

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Bibliographic Details
Published in:Emerging infectious diseases 2011, Vol.17 (1), p.103-106
Main Authors: MULVEY, M.R, GRANT, J.M, PLEWES, K, ROSCOE, D, BOYD, D.A
Format: Article
Language:English
Subjects:
Aged
Anti-Bacterial Agents - pharmacology
bacteria
Bacterial pneumonia
Beta lactamases
beta-Lactamases - genetics
beta-Lactamases - metabolism
Biological and medical sciences
Canada - epidemiology
carbapenemase
Causes of
Dispatch
Distribution
Drug Resistance, Multiple, Bacterial
Escherichia coli
Escherichia coli - drug effects
Escherichia coli - enzymology
Escherichia coli - genetics
Escherichia coli - isolation & purification
Escherichia coli Infections - epidemiology
Escherichia coli Infections - microbiology
Fatal Outcome
Female
Genetic aspects
Health aspects
Humans
India
Klebsiella
Klebsiella Infections - epidemiology
Klebsiella Infections - microbiology
Klebsiella pneumoniae
Klebsiella pneumoniae - drug effects
Klebsiella pneumoniae - enzymology
Klebsiella pneumoniae - genetics
Klebsiella pneumoniae - isolation & purification
Medical sciences
Microbial Sensitivity Tests
Miscellaneous
Multidrug resistance
New Delhi metallo-β-lactamase
Plasmids
Pneumonia
Public health. Hygiene
Public health. Hygiene-occupational medicine
Travel
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Description
Summary:Multidrug-resistant Klebsiella pneumoniae and Escherichia coli isolates harboring New Delhi metallo-β-lactamase (NDM-1) were isolated from a patient who had returned to Canada from India. The NDM-1 gene was found on closely related incompatibility group A/C type plasmids. The occurrence of NDM-1 in North America is a major public health concern.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1701.101358