Application and Development of Megaprostheses in Limb Salvage for Bone Tumors Around the Knee Joint

• Published in: Cancer Control 2022-04, Vol.29, p.10732748221099219-10732748221099219
• Main Author: Zhang, Hao-ran
• Format: Article
• Language: English
• Subjects: Amputation; Bone cancer; Bone implants; Bone Neoplasms - surgery; Bone surgery; Bone tumors; Humans; Knee; Knee Joint - surgery; Limb Salvage; Prosthetics; Review
• ISSN: 1073-2748; 1526-2359; 1073-2748
• DOI: 10.1177/10732748221099219

In recent decades, limb-salvage surgery has replaced amputation as the first choice for the treatment of bone tumors around knee. After tumor resection, there are a variety of reconstruction methods for us to choose, including autograft or allograft, inactivation and reimplantation, artificial prosthesis replacement, and allograft-prosthesis compound reconstruction. Compared with other reconstruction methods, artificial prosthesis reconstruction has some advantages: relatively simple, early weight bearing, fewer early complications, and good function in the early and mid-term follow-up. After decades of continuous improvements, the design of tumor prosthesis has reached a relatively mature stage, and the failure rate of prosthesis has also been declining year by year. However, artificial prostheses also have multiple complications such as infection, aseptic loosening, prosthetic breakage, and patients sometimes face the risk of revision or amputation. Therefore, clinicians need to deeply understand the characteristics of related complications and the principles of treatment.