Dietary Agents and Phytochemicals in the Prevention and Treatment of Experimental Ulcerative Colitis

Inflammatory bowel diseases (IBDs), consisting mainly of ulcerative colitis (UC) and Crohn's disease (CD), are important immune-mediated diseases of the gastrointestinal tract. The etiology of the disease includes environmental and genetic factors. Its management presents a constant challenge f...

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Published in:Journal of Traditional and Complementary Medicine 2014-10, Vol.4 (4), p.203-217
Main Authors: Saxena, Arpit, Kaur, Kamaljeet, Hegde, Shweta, Kalekhan, Faizan M., Baliga, Manjeshwar Shrinath, Fayad, Raja
Format: Article
Language:English
Subjects:
Cancer
Colitis
Colon
Diet therapy
Dietary supplements
Health aspects
Inflammation
Phytochemicals
Prevention
Review
Ulcerative colitis
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Kaur, Kamaljeet
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Fayad, Raja
description Inflammatory bowel diseases (IBDs), consisting mainly of ulcerative colitis (UC) and Crohn's disease (CD), are important immune-mediated diseases of the gastrointestinal tract. The etiology of the disease includes environmental and genetic factors. Its management presents a constant challenge for gastroenterologists and conventional surgeon. 5-Amninosalicylates, antibiotics, steroids, and immune modulators have been used to reduce the symptoms and for maintenance of remission. Unfortunately, long-term usage of these agents has been found to lead to severe toxicities, which are deterrent to the users. Pre-clinical studies carried out in the recent past have shown that certain dietary agents, spices, oils, and dietary phytochemicals that are consumed regularly possess beneficial effects in preventing/ameliorating UC. For the first time, this review addresses the use of these dietary agents and spices in the treatment and prevention of IBD and also emphasizes on the mechanisms responsible for their effects.
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subjects Cancer
Colitis
Colon
Diet therapy
Dietary supplements
Health aspects
Inflammation
Phytochemicals
Prevention
Review
Ulcerative colitis
title Dietary Agents and Phytochemicals in the Prevention and Treatment of Experimental Ulcerative Colitis
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