Analysis of intraocular lens tilt and decentration after cataract surgery in eyes with high myopia using the anterior segment optical coherence tomography

• Published in: Scientific reports 2024-11, Vol.14 (1), p.27987-8, Article 27987
• Main Authors: Jeon, Yoo Young, Park, Nahyun, Lee, Hayoung, Eah, Kyu Sang, Han, Jeewon, Chung, Ho Seok, Kim, Jae Yong, Lee, Hun
• Format: Article
• Language: English
• Subjects: 692/308/409; 692/499; Acuity; Adult; Aged; Anterior chamber; Anterior Eye Segment - diagnostic imaging; Anterior Eye Segment - pathology; Anterior segment optical coherence tomography; Cataract Extraction - adverse effects; Cataracts; Eye lens; Eye surgery; Female; Femtosecond laser assisted cataract surgery; High myopia; Humanities and Social Sciences; Humans; Intraocular lens decentration; Intraocular lens tilt; Intraocular lenses; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Middle Aged; multidisciplinary; Myopia; Myopia - diagnostic imaging; Myopia - pathology; Myopia - surgery; Regression analysis; Retrospective Studies; Science; Science (multidisciplinary); Surgery; Tomography; Tomography, Optical Coherence - methods; Visual Acuity
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-024-78759-8

This retrospective study investigated the degree of intraocular lens (IOL) tilt and decentration after cataract surgery in eyes with varying degrees of myopia using the anterior segment optical coherence tomography (AS-OCT). Eyes of 76 patients were analyzed and divided into three groups: mild myopia (emmetropia to − 1.5 diopter [D], Group 1), moderate myopia (− 1.5 D to − 6.0 D, Group 2), and high myopia (over − 6.0 D, Group 3). Postoperative IOL decentration, tilt, and lens diameter were evaluated using swept-source AS-OCT under mesopic conditions without dilation eyedrop. Postoperative parameters revealed no difference in IOL tilt, but IOL decentration was significantly different among the groups, and the degree of decentration was greater in Group 3 ( P  = 0.007). Univariable regression analysis indicated that age, sex, preoperative uncorrected distant visual acuity, corrected distant visual acuity, intraocular pressure, spherical equivalent, preoperative anterior chamber depth and lens thickness had no influence on postoperative IOL decentration, but axial length (AL) was significantly related to IOL decentration ( P  = 0.001). This association was confirmed using multivariable regression analysis, establishing a significant correlation between AL and IOL decentration ( P  = 0.001) on AS-OCT, showing an increase in IOL decentration associated with increasing AL.