Loading…
Prevalence and risk factors of colonisation with vancomycin-resistant Enterococci faecium upon admission to Germany's largest university hospital
Hospital-acquired infections due to vancomycin-resistant enterococci (VRE) are emerging globally. The aims of our study were to estimate VRE colonisation prevalence in patients upon admission, to determine possible risk factors for VR acquisition that already exist in the outpatient setting, and to...
Saved in:
Published in: | GMS hygiene and infection control 2021, Vol.16, p.Doc06 |
---|---|
Main Authors: | , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | Hospital-acquired infections due to vancomycin-resistant enterococci (VRE) are emerging globally. The aims of our study were to estimate VRE colonisation prevalence in patients upon admission, to determine possible risk factors for VR
acquisition that already exist in the outpatient setting, and to monitor whether VRE-colonised patients developed a VRE infection during their current hospital stay.
In 2014 and 2015, patients admitted to non-intensive care units were screened for rectal VRE carriage. The study patients filled out a questionnaire on potential risk factors. Analyses were restricted to VR
carriage. All patients with VRE colonisation were retrospectively monitored for infections with VRE during their current hospital stay.
In 4,013 enrolled patients, the VRE colonisation prevalence upon admission was 1.2% (n=48), and colonisation prevalence was 1.1% (n=45) for VR
. Only one VRE-colonised patient developed an infection with the detection of a VRE, among others. Colonisation with VR
was associated with current antibiotic use. Risk factors of VR
colonisation upon admission were increasing age, previous colonisation or infection with multidrug resistant organisms, sampling year 2015, and, within the previous six months, antibiotic exposure, a stay at a rehabilitation center, and a hospital stay.
We observed that antibiotic treatment which occurred prior admission influenced VR
prevalence upon admission. Thus, wise antibiotic use in outpatient settings plays a major role in the prevention of VR
acquisition. |
---|---|
ISSN: | 2196-5226 2196-5226 |
DOI: | 10.3205/dgkh000377 |