Exacerbation of collagen induced arthritis by Fcγ receptor targeted collagen peptide due to enhanced inflammatory chemokine and cytokine production

Clarifies the mechanism of immune complex-mediated inflammation and modulation of collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA), and specifically the roles played by antibodies specific for bovine type II collagen (CII) and Fcγ receptors. Source: National Library of Ne...

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Bibliographic Details
Published in:Biologics 2012-01, Vol.6 (default), p.101-115
Main Author: Szarka, Eszter
Format: Article
Language:English
Subjects:
Arthritis
Chemokines
Collagen
Collagen diseases
Cytokines
Epitopes
Health aspects
Inflammation
Original Research
Peptides
Physiological aspects
Rheumatoid arthritis
Risk factors
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Summary:Clarifies the mechanism of immune complex-mediated inflammation and modulation of collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA), and specifically the roles played by antibodies specific for bovine type II collagen (CII) and Fcγ receptors. Source: National Library of New Zealand Te Puna Matauranga o Aotearoa, licensed by the Department of Internal Affairs for re-use under the Creative Commons Attribution 3.0 New Zealand Licence.
ISSN:1177-5475
1177-5491
1177-5491
1177-5475
DOI:10.2147/BTT.S29749