High postoperative serum levels of surfactant type B as novel prognostic markers for congenital heart surgery

Objective: Congenital heart diseases are observed in 5 to 8 of every 1000 live births. The presence of a valuable biomarker during the surgical periods may aid the clinician in a more accurate prognosis during treatment. Methods: For this reason, surfactant protein B plasma levels may help to evalua...

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Bibliographic Details
Published in:Revista brasileira de cirurgia cardiovascular 2014-04, Vol.29 (2), p.186-191
Main Authors: Isık, Onur, Disli, Olcay Murat, Bas, Tolga, Aydın, Hakan, Koç, Murat, Kutsal, Ali
Format: Article
Language:English
Subjects:
CARDIAC & CARDIOVASCULAR SYSTEMS
Cardiology
Cardiopatias Congênitas
Cirurgia Torácica
Heart surgery
Marcadores Biológicos
Proteína B Associada a Surfactante Pulmonar
SURGERY
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Summary:Objective: Congenital heart diseases are observed in 5 to 8 of every 1000 live births. The presence of a valuable biomarker during the surgical periods may aid the clinician in a more accurate prognosis during treatment. Methods: For this reason, surfactant protein B plasma levels may help to evaluate patients with cardiac problems diminishing the alveolocapillary membrane stability. In this study, plasma levels of this biomarker were measured in the preoperative and postoperative periods. This study was conducted to detect the differences between pulmonary hypertensive and normotensive patients. The differences before and after cardiopulmonary bypass were examined. Results: The differences in cardiopulmonary bypass time, cross-clamp time , inotropic support dose, and duration of intensive care of patients with and without pulmonary hypertensive were found to be statistically significant (P
ISSN:0102-7638
1678-9741
1678-9741
DOI:10.5935/1678-9741.20140039