Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs

We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of Ornithogalum plant mate...

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Bibliographic Details
Published in:Toxicon X 2019-10, Vol.4, p.100014-100014, Article 100014
Main Authors: Slenter, Inge J.M., Djajadiningrat-Laanen, Sylvia C., de Vries, Irma, Dijkman, Marieke A.
Format: Article
Language:English
Subjects:
Blindness
Cardiac glycosides
Ornithogalum arabicum
Retinal degeneration
Short Communication
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Summary:We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of Ornithogalum plant material can be potentially life-threatening to companion animals. Further studies are necessary to confirm the involvement of cardiac glycoside-like toxins present in Ornithogalum arabicum and the toxicity of these substances to the retina. •Intoxication with Ornithogalum arabicum leads to visual impairment and irreversible blindness in dogs.•Intoxication with Ornithogalum arabicum may be life-threatening in companion animals.•Ornithogalum arabicum and other species are suspected to contain heart glycosides.
ISSN:2590-1710
2590-1710
DOI:10.1016/j.toxcx.2019.100014