Loading…
Mid-Term Results after Lateral Transfibular Approach Total Ankle Arthroplasty
Category: Ankle Arthritis; Ankle Introduction/Purpose: Continued improvements in total ankle arthroplasty (TAA) implant design have led to promising clinical outcomes. The lateral transfibular approach TAA allows for excellent visualization of the center of rotation of the ankle and allows for corre...
Saved in:
Published in: | Foot & ankle orthopaedics 2022-01, Vol.7 (1), p.2473011421S00151 |
---|---|
Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | |
---|---|
cites | |
container_end_page | |
container_issue | 1 |
container_start_page | 2473011421S00151 |
container_title | Foot & ankle orthopaedics |
container_volume | 7 |
creator | Coleman, Michelle M. Abousayed, Mostafa Netto, Cesar de Cesar Lee, Moses Maccario, Camilla Sherman, Thomas I. Schon, Lew C. |
description | Category:
Ankle Arthritis; Ankle
Introduction/Purpose:
Continued improvements in total ankle arthroplasty (TAA) implant design have led to promising clinical outcomes. The lateral transfibular approach TAA allows for excellent visualization of the center of rotation of the ankle and allows for correction of rotational and sagittal deformity by shortening or lengthening of the fibula. Furthermore, the curved implant design allows for minimal bony resection. The purpose of this study is to report the medium-term clinical and radiographic results for consecutive patients who underwent the lateral approach TAA.
Methods:
IRB approval was obtained for this study. Consecutive patients who underwent lateral approach TAA for tibiotalar arthritis by a single surgeon were enrolled on a prospective basis from January 2013 to June 2015. This time period represented the initial case series of TAA performed by the surgeon. Patient reported outcomes (PROs) were collected including the Ankle Osteoarthritis Scale (AOS), 12-item short-form survey (SF-12), and Visual Analogue Pain Scale (VAS). The need for subsequent procedures was recorded. Radiographs were evaluated for preoperative and postoperative alignment using the lateral distal tibial angle (LDTA), tibiotalar surface angle (TTS), anterior distal tibia angle (ADTA), and the lateral talar station (LTS). Radiographs were also evaluated for the development of peri-implant lucency and subsidence. Data was tested for normality. T-tests were used to determine differences between preoperative data and postoperative data. A p |
doi_str_mv | 10.1177/2473011421S00151 |
format | article |
fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_1a5e786cd17942dabb3dd2845faec585</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_2473011421S00151</sage_id><doaj_id>oai_doaj_org_article_1a5e786cd17942dabb3dd2845faec585</doaj_id><sourcerecordid>2651990847</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3631-d8ee96e2d297b6fc2f70ba6f5c05f2061017fe7dd62f6ca0f6e1e23c8e0ae3a03</originalsourceid><addsrcrecordid>eNp1kUFr3DAQhUVpacI295yKoWc3kmxJ1qWwhDYNbCi0m7MYS6Ndb72WK9mF_Ptos2maFHrRiJk338zwCDln9CNjSl3wWlWUsZqzH5QywV6R00OqPOReP_ufkLOUdjRrlNC6ad6Sk0pQrWTNT8nNTefKNcZ98R3T3E-pAD9hLFaQX-iLdYQh-a6de4jFchxjALst1mHKteXws8diGadtDGMPabp7R9546BOePcYFuf3yeX35tVx9u7q-XK5KW8mKla5B1BK541q10lvuFW1BemGp8JxKllf1qJyT3EsL1EtkyCvbIAWsgFYLcn3kugA7M8ZuD_HOBOjMQyLEjYE4dbZHw0CgaqR1TOmaO2jbyjne1MIDWtGIzPp0ZI1zu0dncZjy4S-gLytDtzWb8Ns0GajVAfDhERDDrxnTZHZhjkO-33ApmNa0yVYsCD2qbAwpRfRPExg1Bz_Nv37mlvfPN3tq-ONeFpRHQYIN_p36X-A9gSCojw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2651990847</pqid></control><display><type>article</type><title>Mid-Term Results after Lateral Transfibular Approach Total Ankle Arthroplasty</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>Sage Journals GOLD Open Access 2024</source><source>PubMed Central</source><creator>Coleman, Michelle M. ; Abousayed, Mostafa ; Netto, Cesar de Cesar ; Lee, Moses ; Maccario, Camilla ; Sherman, Thomas I. ; Schon, Lew C.</creator><creatorcontrib>Coleman, Michelle M. ; Abousayed, Mostafa ; Netto, Cesar de Cesar ; Lee, Moses ; Maccario, Camilla ; Sherman, Thomas I. ; Schon, Lew C.</creatorcontrib><description>Category:
Ankle Arthritis; Ankle
Introduction/Purpose:
Continued improvements in total ankle arthroplasty (TAA) implant design have led to promising clinical outcomes. The lateral transfibular approach TAA allows for excellent visualization of the center of rotation of the ankle and allows for correction of rotational and sagittal deformity by shortening or lengthening of the fibula. Furthermore, the curved implant design allows for minimal bony resection. The purpose of this study is to report the medium-term clinical and radiographic results for consecutive patients who underwent the lateral approach TAA.
Methods:
IRB approval was obtained for this study. Consecutive patients who underwent lateral approach TAA for tibiotalar arthritis by a single surgeon were enrolled on a prospective basis from January 2013 to June 2015. This time period represented the initial case series of TAA performed by the surgeon. Patient reported outcomes (PROs) were collected including the Ankle Osteoarthritis Scale (AOS), 12-item short-form survey (SF-12), and Visual Analogue Pain Scale (VAS). The need for subsequent procedures was recorded. Radiographs were evaluated for preoperative and postoperative alignment using the lateral distal tibial angle (LDTA), tibiotalar surface angle (TTS), anterior distal tibia angle (ADTA), and the lateral talar station (LTS). Radiographs were also evaluated for the development of peri-implant lucency and subsidence. Data was tested for normality. T-tests were used to determine differences between preoperative data and postoperative data. A p<0.05 was considered significant.
Results:
53 patients who underwent 59 TAA procedures were included. Average follow-up was 5.7 +/- 0.9 years. Average age was 53 +/- 7.0. Comorbidities included smoking (11/53), diabetes (6/53), and prior procedures (33/53). Sixteen ankles (27%) underwent one or more subsequent procedures including gutter debridement (7/59), debridement for periprosthetic infection (3/59), and removal of hardware (7/59). All fibular osteotomies healed. Four ankles had asymptomatic peri-implant lucency or cysts (4/59). No patients had subsidence or required revision of the tibial or talar components. Coronal and sagittal alignment were significantly improved for all measures (p<0.05). VAS scores improved from a mean of 7.5 preoperatively to 1 at final follow- up (p<0.0001). SF-12 physical component scores improved from 34 to 41.5 (p=0.0227). AOS scores improved from 54.8 to 19.1 (p<0.0001).
Conclusion:
At medium term follow-up, patient reported outcomes remain significantly improved in patients after lateral approach TAA. There were very few radiographic findings of lucency and cyst formation, and all of these were asymptomatic. No revision of metal implants was required. Excellent deformity correction was achieved. The rate of subsequent procedures was high, although the rate of actual component revision was 0%. Lateral approach TAA appears to have overall good outcomes at medium term follow-up.</description><identifier>ISSN: 2473-0114</identifier><identifier>EISSN: 2473-0114</identifier><identifier>DOI: 10.1177/2473011421S00151</identifier><identifier>PMID: 35097642</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Ankle ; Arthritis ; Asymptomatic ; Debridement ; Joint surgery ; Patients ; Transplants & implants</subject><ispartof>Foot & ankle orthopaedics, 2022-01, Vol.7 (1), p.2473011421S00151</ispartof><rights>The Author(s) 2022</rights><rights>The Author(s) 2022. This work is licensed under the Creative Commons Attribution – Non-Commercial License https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2022 2022 American Orthopaedic Foot & Ankle Society, unless otherwise noted. Manuscript content on this site is licensed under Creative Commons Licenses.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794975/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2651990847?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,21966,25753,27853,27924,27925,37012,44590,44945,45333,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35097642$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Coleman, Michelle M.</creatorcontrib><creatorcontrib>Abousayed, Mostafa</creatorcontrib><creatorcontrib>Netto, Cesar de Cesar</creatorcontrib><creatorcontrib>Lee, Moses</creatorcontrib><creatorcontrib>Maccario, Camilla</creatorcontrib><creatorcontrib>Sherman, Thomas I.</creatorcontrib><creatorcontrib>Schon, Lew C.</creatorcontrib><title>Mid-Term Results after Lateral Transfibular Approach Total Ankle Arthroplasty</title><title>Foot & ankle orthopaedics</title><addtitle>Foot Ankle Orthop</addtitle><description>Category:
Ankle Arthritis; Ankle
Introduction/Purpose:
Continued improvements in total ankle arthroplasty (TAA) implant design have led to promising clinical outcomes. The lateral transfibular approach TAA allows for excellent visualization of the center of rotation of the ankle and allows for correction of rotational and sagittal deformity by shortening or lengthening of the fibula. Furthermore, the curved implant design allows for minimal bony resection. The purpose of this study is to report the medium-term clinical and radiographic results for consecutive patients who underwent the lateral approach TAA.
Methods:
IRB approval was obtained for this study. Consecutive patients who underwent lateral approach TAA for tibiotalar arthritis by a single surgeon were enrolled on a prospective basis from January 2013 to June 2015. This time period represented the initial case series of TAA performed by the surgeon. Patient reported outcomes (PROs) were collected including the Ankle Osteoarthritis Scale (AOS), 12-item short-form survey (SF-12), and Visual Analogue Pain Scale (VAS). The need for subsequent procedures was recorded. Radiographs were evaluated for preoperative and postoperative alignment using the lateral distal tibial angle (LDTA), tibiotalar surface angle (TTS), anterior distal tibia angle (ADTA), and the lateral talar station (LTS). Radiographs were also evaluated for the development of peri-implant lucency and subsidence. Data was tested for normality. T-tests were used to determine differences between preoperative data and postoperative data. A p<0.05 was considered significant.
Results:
53 patients who underwent 59 TAA procedures were included. Average follow-up was 5.7 +/- 0.9 years. Average age was 53 +/- 7.0. Comorbidities included smoking (11/53), diabetes (6/53), and prior procedures (33/53). Sixteen ankles (27%) underwent one or more subsequent procedures including gutter debridement (7/59), debridement for periprosthetic infection (3/59), and removal of hardware (7/59). All fibular osteotomies healed. Four ankles had asymptomatic peri-implant lucency or cysts (4/59). No patients had subsidence or required revision of the tibial or talar components. Coronal and sagittal alignment were significantly improved for all measures (p<0.05). VAS scores improved from a mean of 7.5 preoperatively to 1 at final follow- up (p<0.0001). SF-12 physical component scores improved from 34 to 41.5 (p=0.0227). AOS scores improved from 54.8 to 19.1 (p<0.0001).
Conclusion:
At medium term follow-up, patient reported outcomes remain significantly improved in patients after lateral approach TAA. There were very few radiographic findings of lucency and cyst formation, and all of these were asymptomatic. No revision of metal implants was required. Excellent deformity correction was achieved. The rate of subsequent procedures was high, although the rate of actual component revision was 0%. Lateral approach TAA appears to have overall good outcomes at medium term follow-up.</description><subject>Ankle</subject><subject>Arthritis</subject><subject>Asymptomatic</subject><subject>Debridement</subject><subject>Joint surgery</subject><subject>Patients</subject><subject>Transplants & implants</subject><issn>2473-0114</issn><issn>2473-0114</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>AFRWT</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp1kUFr3DAQhUVpacI295yKoWc3kmxJ1qWwhDYNbCi0m7MYS6Ndb72WK9mF_Ptos2maFHrRiJk338zwCDln9CNjSl3wWlWUsZqzH5QywV6R00OqPOReP_ufkLOUdjRrlNC6ad6Sk0pQrWTNT8nNTefKNcZ98R3T3E-pAD9hLFaQX-iLdYQh-a6de4jFchxjALst1mHKteXws8diGadtDGMPabp7R9546BOePcYFuf3yeX35tVx9u7q-XK5KW8mKla5B1BK541q10lvuFW1BemGp8JxKllf1qJyT3EsL1EtkyCvbIAWsgFYLcn3kugA7M8ZuD_HOBOjMQyLEjYE4dbZHw0CgaqR1TOmaO2jbyjne1MIDWtGIzPp0ZI1zu0dncZjy4S-gLytDtzWb8Ns0GajVAfDhERDDrxnTZHZhjkO-33ApmNa0yVYsCD2qbAwpRfRPExg1Bz_Nv37mlvfPN3tq-ONeFpRHQYIN_p36X-A9gSCojw</recordid><startdate>20220101</startdate><enddate>20220101</enddate><creator>Coleman, Michelle M.</creator><creator>Abousayed, Mostafa</creator><creator>Netto, Cesar de Cesar</creator><creator>Lee, Moses</creator><creator>Maccario, Camilla</creator><creator>Sherman, Thomas I.</creator><creator>Schon, Lew C.</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><general>SAGE Publishing</general><scope>AFRWT</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20220101</creationdate><title>Mid-Term Results after Lateral Transfibular Approach Total Ankle Arthroplasty</title><author>Coleman, Michelle M. ; Abousayed, Mostafa ; Netto, Cesar de Cesar ; Lee, Moses ; Maccario, Camilla ; Sherman, Thomas I. ; Schon, Lew C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3631-d8ee96e2d297b6fc2f70ba6f5c05f2061017fe7dd62f6ca0f6e1e23c8e0ae3a03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Ankle</topic><topic>Arthritis</topic><topic>Asymptomatic</topic><topic>Debridement</topic><topic>Joint surgery</topic><topic>Patients</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Coleman, Michelle M.</creatorcontrib><creatorcontrib>Abousayed, Mostafa</creatorcontrib><creatorcontrib>Netto, Cesar de Cesar</creatorcontrib><creatorcontrib>Lee, Moses</creatorcontrib><creatorcontrib>Maccario, Camilla</creatorcontrib><creatorcontrib>Sherman, Thomas I.</creatorcontrib><creatorcontrib>Schon, Lew C.</creatorcontrib><collection>Sage Journals GOLD Open Access 2024</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Foot & ankle orthopaedics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Coleman, Michelle M.</au><au>Abousayed, Mostafa</au><au>Netto, Cesar de Cesar</au><au>Lee, Moses</au><au>Maccario, Camilla</au><au>Sherman, Thomas I.</au><au>Schon, Lew C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mid-Term Results after Lateral Transfibular Approach Total Ankle Arthroplasty</atitle><jtitle>Foot & ankle orthopaedics</jtitle><addtitle>Foot Ankle Orthop</addtitle><date>2022-01-01</date><risdate>2022</risdate><volume>7</volume><issue>1</issue><spage>2473011421S00151</spage><pages>2473011421S00151-</pages><issn>2473-0114</issn><eissn>2473-0114</eissn><abstract>Category:
Ankle Arthritis; Ankle
Introduction/Purpose:
Continued improvements in total ankle arthroplasty (TAA) implant design have led to promising clinical outcomes. The lateral transfibular approach TAA allows for excellent visualization of the center of rotation of the ankle and allows for correction of rotational and sagittal deformity by shortening or lengthening of the fibula. Furthermore, the curved implant design allows for minimal bony resection. The purpose of this study is to report the medium-term clinical and radiographic results for consecutive patients who underwent the lateral approach TAA.
Methods:
IRB approval was obtained for this study. Consecutive patients who underwent lateral approach TAA for tibiotalar arthritis by a single surgeon were enrolled on a prospective basis from January 2013 to June 2015. This time period represented the initial case series of TAA performed by the surgeon. Patient reported outcomes (PROs) were collected including the Ankle Osteoarthritis Scale (AOS), 12-item short-form survey (SF-12), and Visual Analogue Pain Scale (VAS). The need for subsequent procedures was recorded. Radiographs were evaluated for preoperative and postoperative alignment using the lateral distal tibial angle (LDTA), tibiotalar surface angle (TTS), anterior distal tibia angle (ADTA), and the lateral talar station (LTS). Radiographs were also evaluated for the development of peri-implant lucency and subsidence. Data was tested for normality. T-tests were used to determine differences between preoperative data and postoperative data. A p<0.05 was considered significant.
Results:
53 patients who underwent 59 TAA procedures were included. Average follow-up was 5.7 +/- 0.9 years. Average age was 53 +/- 7.0. Comorbidities included smoking (11/53), diabetes (6/53), and prior procedures (33/53). Sixteen ankles (27%) underwent one or more subsequent procedures including gutter debridement (7/59), debridement for periprosthetic infection (3/59), and removal of hardware (7/59). All fibular osteotomies healed. Four ankles had asymptomatic peri-implant lucency or cysts (4/59). No patients had subsidence or required revision of the tibial or talar components. Coronal and sagittal alignment were significantly improved for all measures (p<0.05). VAS scores improved from a mean of 7.5 preoperatively to 1 at final follow- up (p<0.0001). SF-12 physical component scores improved from 34 to 41.5 (p=0.0227). AOS scores improved from 54.8 to 19.1 (p<0.0001).
Conclusion:
At medium term follow-up, patient reported outcomes remain significantly improved in patients after lateral approach TAA. There were very few radiographic findings of lucency and cyst formation, and all of these were asymptomatic. No revision of metal implants was required. Excellent deformity correction was achieved. The rate of subsequent procedures was high, although the rate of actual component revision was 0%. Lateral approach TAA appears to have overall good outcomes at medium term follow-up.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>35097642</pmid><doi>10.1177/2473011421S00151</doi><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2473-0114 |
ispartof | Foot & ankle orthopaedics, 2022-01, Vol.7 (1), p.2473011421S00151 |
issn | 2473-0114 2473-0114 |
language | eng |
recordid | cdi_doaj_primary_oai_doaj_org_article_1a5e786cd17942dabb3dd2845faec585 |
source | Publicly Available Content Database (Proquest) (PQ_SDU_P3); Sage Journals GOLD Open Access 2024; PubMed Central |
subjects | Ankle Arthritis Asymptomatic Debridement Joint surgery Patients Transplants & implants |
title | Mid-Term Results after Lateral Transfibular Approach Total Ankle Arthroplasty |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T16%3A16%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mid-Term%20Results%20after%20Lateral%20Transfibular%20Approach%20Total%20Ankle%20Arthroplasty&rft.jtitle=Foot%20&%20ankle%20orthopaedics&rft.au=Coleman,%20Michelle%20M.&rft.date=2022-01-01&rft.volume=7&rft.issue=1&rft.spage=2473011421S00151&rft.pages=2473011421S00151-&rft.issn=2473-0114&rft.eissn=2473-0114&rft_id=info:doi/10.1177/2473011421S00151&rft_dat=%3Cproquest_doaj_%3E2651990847%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3631-d8ee96e2d297b6fc2f70ba6f5c05f2061017fe7dd62f6ca0f6e1e23c8e0ae3a03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2651990847&rft_id=info:pmid/35097642&rft_sage_id=10.1177_2473011421S00151&rfr_iscdi=true |