Apremilast in people living with HIV with psoriasis vulgaris: A case report

Psoriasis is a chronic papulosquamous skin disease that involves immune-mediated cutaneous inflammation and keratinocyte hyperproliferation. The associated immunosuppression in people living with HIV (PLHIV) with psoriasis poses a challenge to the clinician as therapeutic options are limited. Until...

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Bibliographic Details
Published in:Indian journal of dermatology 2019-05, Vol.64 (3), p.242-244
Main Authors: Shah, Bela, Mistry, Deval, Chaudhary, Navin
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Apremilast
Care and treatment
Case Report
Case reports
Cytokines
Efavirenz
Health aspects
Hepatitis
HIV
HIV patients
Human immunodeficiency virus
Immunotherapy
Infections
Laboratories
Lymphocytes
Patients
Psoriasis
Skin
Skin diseases
Tumor necrosis factor-TNF
Ustekinumab
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Description
Summary:Psoriasis is a chronic papulosquamous skin disease that involves immune-mediated cutaneous inflammation and keratinocyte hyperproliferation. The associated immunosuppression in people living with HIV (PLHIV) with psoriasis poses a challenge to the clinician as therapeutic options are limited. Until now, there have been no documented case of apremilast therapy for HIV-associated psoriasis in India. Here, we report a case of HIV-associated psoriasis who achieved Psoriasis Area and Severity Index (PASI) 100 with apremilast therapy.
ISSN:0019-5154
1998-3611
DOI:10.4103/ijd.IJD_633_18