Estradiol and luteinizing hormone concentrations in the follicular aspirate during ovum pickup as predictors of in vitro fertilization (IVF) outcome

Background: A relationship between ‘oocyte quality’ and follicular fluid hormones is expected, since its formation coincides with the ‘oocyte maturation’ phase. The aim of this study was to find a possible relation between oocyte quality with follicular luteinizing hormone (LH) and estradiol (E2) as...

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Bibliographic Details
Published in:Middle East Fertility Society journal 2017-03, Vol.22 (1), p.27-32
Main Authors: Sarhan, Diaa, El Mazny, Akmal, Taha, Tamer, Aziz, Amira, Azmy, Osama, Fakhry, Dawood, Torky, Haitham
Format: Article
Language:English
Subjects:
Follicular fluid
Hormones
Oocyte quality
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Summary:Background: A relationship between ‘oocyte quality’ and follicular fluid hormones is expected, since its formation coincides with the ‘oocyte maturation’ phase. The aim of this study was to find a possible relation between oocyte quality with follicular luteinizing hormone (LH) and estradiol (E2) as hormonal parameters of oocyte quality during ovum pickup for intra-cytoplasmic sperm injection (ICSI). Methods: Concentrations of LH and E2 in individual follicular fluid samples obtained during assisted reproduction treatment were related to oocyte nuclear maturation, fertilization and embryo grading. E2 and LH differences between individual groups of oocytes and embryos were calculated using the paired Student’s t test and ANOVA test. Results: Follicular E2 levels showed a significant positive correlation with oocyte nuclear maturation, fertilization and embryo grading being higher in follicles whose oocytes had matured nucleus (475±142.9ng/ml vs. 332±76.4ng/ml, P value
ISSN:1110-5690
DOI:10.1016/j.mefs.2016.09.005