Assessment of foraminal decompression following discoplasty using a combination of ex vivo testing and numerical tools

• Published in: Scientific reports 2023-02, Vol.13 (1), p.3293-3293, Article 3293
• Main Authors: Techens, Chloé, Bereczki, Ferenc, Montanari, Sara, Lazary, Aron, Cristofolini, Luca, Eltes, Peter Endre
• Format: Article
• Language: English
• Subjects: 639/166/985; 692/698/1671; Biomechanics; Bone Cements; Bone implants; Cadavers; Cement; Decompression; Geometry; Humanities and Social Sciences; Humans; Intervertebral Disc; Intervertebral discs; Lumbar Vertebrae; Medical imaging; Motion; multidisciplinary; Nucleus pulposus; Pain; Patients; Polymethyl methacrylate; Science; Science (multidisciplinary); Spine; Surgery; Surgical techniques; Tomography, X-Ray Computed
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-27552-0

Percutaneous Cement Discoplasty (PCD) is a minimally invasive surgical technique to treat degenerated intervertebral discs. When the disc is severely degenerated, the vacuum observed in place of the nucleus pulposus can be filled with bone cement to restore the disc height, open the foramen space, and relieve pain. This study aimed to evaluate the foramen geometry change due to PCD, in the loaded spine. Cadaveric spines (n = 25) were tested in flexion and extension while Digital Image Correlation (DIC) measured displacements and deformations. Tests were performed on simulated pre-operative condition (nucleotomy) and after PCD. Registering DIC images and the 3D specimen geometry from CT scans, a 3D model of the specimens aligned in the experimental pose was obtained for nucleotomy and PCD. Foramen space volume was geometrically measured for both conditions. The volume of cement injected was measured to explore correlation with the change of foramen space. PCD induced a significant overall foraminal decompression in both flexion (foramen space increased by 835 ± 1289 mm 3 , p  = 0.001) and extension (1205 ± 1106 mm 3 , p