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Emergency management of a 13-year-old patient with primary mediastinal B cell lymphoma: Extracorporeal membrane oxygenation and superior vena cava stent prior to chemotherapy

Primary mediastinal B cell lymphoma (PMBCL) is a rare type of non-Hodgkin's lymphoma, and prompt diagnosis and initiation of chemotherapy are necessary to limit compression of cardiovascular structures. A 13-year-old patient was diagnosed with PMBCL, resulting in acute hypoxemic respiratory fai...

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Published in:Pediatric hematology oncology journal 2024-09, Vol.9 (3), p.129-132
Main Authors: Maffei, Salvador R., Stapleton, Gary, Doane, Katherine, Thomas, James, Tcharmtchi, M Hossein, Brackett, Julienne, Bhar, Saleh
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container_end_page 132
container_issue 3
container_start_page 129
container_title Pediatric hematology oncology journal
container_volume 9
creator Maffei, Salvador R.
Stapleton, Gary
Doane, Katherine
Thomas, James
Tcharmtchi, M Hossein
Brackett, Julienne
Bhar, Saleh
description Primary mediastinal B cell lymphoma (PMBCL) is a rare type of non-Hodgkin's lymphoma, and prompt diagnosis and initiation of chemotherapy are necessary to limit compression of cardiovascular structures. A 13-year-old patient was diagnosed with PMBCL, resulting in acute hypoxemic respiratory failure and cardiogenic shock with clinical pericardial tamponade. Chemotherapy was initiated after veno-arterial extracorporeal membrane oxygenation and subsequent endovascular stenting of the superior vena cava (SVC) to optimize cardiac output due to malignant SVC syndrome. We discuss the challenges of diagnosis and emergency management of pediatric patients with PMBCL and review the existing relevant literature for SVC syndrome secondary to PMBCL.
doi_str_mv 10.1016/j.phoj.2024.03.010
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subjects Extracorporeal membrane oxygenation
Interventional cardiology
Mediastinal mass
Superior vena cava syndrome
title Emergency management of a 13-year-old patient with primary mediastinal B cell lymphoma: Extracorporeal membrane oxygenation and superior vena cava stent prior to chemotherapy
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