Chemical and Biological Properties of Biochanin A and Its Pharmaceutical Applications

Biochanin A (BCA), an isoflavone derived from various plants such as chickpea, red clover and soybean, is attracting increasing attention and is considered to have applications in the development of pharmaceuticals and nutraceuticals due to its anti-inflammatory, anti-oxidant, anti-cancer and neurop...

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Bibliographic Details
Published in:Pharmaceutics 2023-03, Vol.15 (4), p.1105
Main Authors: Feng, Zhen-Jie, Lai, Wing-Fu
Format: Article
Language:English
Subjects:
Alzheimer's disease
Antimicrobial agents
Beans
Bioavailability
biochanin A
Biological activity
Bone cancer
Cell cycle
Chemical properties
Chickpea
chickpeas
Chlamydia
Chromatography
Diabetes
extraction
Head & neck cancer
Health aspects
isoflavone
Isoflavones
Kinases
Lung cancer
metabolism
Pharmaceutical research
Physiology
Plant products
Proteins
Red clover
Review
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Summary:Biochanin A (BCA), an isoflavone derived from various plants such as chickpea, red clover and soybean, is attracting increasing attention and is considered to have applications in the development of pharmaceuticals and nutraceuticals due to its anti-inflammatory, anti-oxidant, anti-cancer and neuroprotective properties. To design optimised and targeted BCA formulations, on one hand there is a need for more in-depth studies on the biological functions of BCA. On the other hand, further studies on the chemical conformation, metabolic composition and bioavailability of BCA need to be conducted. This review highlights the various biological functions, extraction methods, metabolism, bioavailability, and application prospects of BCA. It is hoped that this review will provide a basis for understanding the mechanism, safety and toxicity of BCA and implementing the development of BCA formulations.
ISSN:1999-4923
1999-4923
DOI:10.3390/pharmaceutics15041105