Dendrimers for theranostic applications

Recently, there have been tremendous advances in the development of various nanotechnology-based platforms for diagnosis and therapy. These nanoplatforms, which include liposomes, micelles, polymers, and dendrimers, comprise highly integrated nanoparticles that provide multiple functions, such as ta...

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Bibliographic Details
Published in:Biomolecular concepts 2015-06, Vol.6 (3), p.205-217
Main Authors: Sk, Ugir Hossain, Kojima, Chie
Format: Article
Language:English
Subjects:
dendrimer
drug delivery
gene delivery
imaging
Medical imaging
theranostic
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Summary:Recently, there have been tremendous advances in the development of various nanotechnology-based platforms for diagnosis and therapy. These nanoplatforms, which include liposomes, micelles, polymers, and dendrimers, comprise highly integrated nanoparticles that provide multiple functions, such as targeting, imaging, and therapy. This review focuses on dendrimer-based nanocarriers that have recently been developed for ‘theranostics (or theragnosis)’, a combination of therapy and diagnostics. We discuss the and applications of these nanocarriers in strategies against diseases including cancer. We also explore the use of dendrimers as imaging agents for fluorescence imaging, magnetic resonance imaging, X-ray computed tomography, and nuclear medical imaging.
ISSN:1868-5021
1868-5021
1868-503X
DOI:10.1515/bmc-2015-0012