The efficacy and nephrotoxicity associated with colistin use in an intensive care unit in Vietnam: Use of colistin in a population of lower body weight

Highlights • Efficacy and nephrotoxicity of Colistin was evaluated among Vietnamese patients. • The study was conducted in a population of lower body weight (median 53 ± 8.6 kg). • A personalized dosing protocol of colistin was used. • The incidence of nephrotoxicity was 21% per RIFLE criteria....

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Bibliographic Details
Published in:International journal of infectious diseases 2015-06, Vol.35 (C), p.18-23
Main Authors: Binh, Nguyen Gia, Hayakawa, Kayoko, Co, Dao Xuan, Tuan, Nguyen Dang, Anh, Nguyen Hoang, Thuy, Nguyen Thi Hong, Phuong, Doan Mai, Huong, Nguyen Thi Lien, Thuy, Pham Thi Phuong, Chau, Ngo Qui, Nhung, Pham Hong, Gam, Do Thi Hong, Hai, Duong Thanh, Huong, Tran Thu, Van Anh, Le, Takeshita, Nozomi, Ohmagari, Norio
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - adverse effects
Anti-Bacterial Agents - therapeutic use
Asia
Colistin
Colistin - administration & dosage
Colistin - adverse effects
Colistin - therapeutic use
Critical Illness
Female
Hospital acquired infection
Humans
ICU
Infectious Disease
Intensive Care Units
Kidney - drug effects
Lower body weight
Male
Middle Aged
Nephrotoxicity
Pulmonary/Respiratory
Retrospective Studies
Thinness
Vietnam
Young Adult
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Summary:Highlights • Efficacy and nephrotoxicity of Colistin was evaluated among Vietnamese patients. • The study was conducted in a population of lower body weight (median 53 ± 8.6 kg). • A personalized dosing protocol of colistin was used. • The incidence of nephrotoxicity was 21% per RIFLE criteria.
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2015.03.020