Preliminary report of Iranian Registry of Alzheimer's disease in Tehran province: A cross‐sectional study in Iran

Background and Aims Alzheimer's disease (AD) is the main cause of dementia and over the 55 million people live with dementia worldwide. We aimed to establish the first database called the Iranian Alzheimer's Disease Registry to create a powerful source for future research in the country. I...

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Published in:Health science reports 2022-11, Vol.5 (6), p.e952-n/a
Main Authors: Fahanik‐Babaei, Javad, Sedighi, Mohsen, Mehrabi, Soraya, Pournik, Omid, Sheikh Taheri, Abbas, Kamalzadeh, Leila, Zarei, Mahsa, Roghani, Mehrdad, Golab, Fereshteh, Almasi, Mostafa, Etezadi, Afshin, Afshin‐Majd, Siamak, Malakouti, Seyed Kazem, Rajabi, Majid, Moghaddasi, Mehdi, Hajati, Gholamreza, Golmohammadi Khamne, Fatemeh, Jafari, Arzhang, Amanollahi, Alireza, Baluchnejadmojarad, Tourandokht
Format: Article
Language:English
Subjects:
Alzheimer disease
Alzheimer's disease
Angina pectoris
Brain research
Caregivers
Cognitive ability
Cross-sectional studies
data collection
Dementia
disease management
Family medical history
Laboratories
Neurodegeneration
Neuropsychology
Older people
Parkinson's disease
Patients
Public health
Questionnaires
registries
Traumatic brain injury
Womens health
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Summary:Background and Aims Alzheimer's disease (AD) is the main cause of dementia and over the 55 million people live with dementia worldwide. We aimed to establish the first database called the Iranian Alzheimer's Disease Registry to create a powerful source for future research in the country. In this report, the design and early results of the Iranian Alzheimer's Disease Registry will be described. Methods We performed this multicenter investigation and patients' data including age, sex, educational level, disease status, Mini‐Mental State Examination (MMSE), and Geriatric Depression Scale (GDS) from 2018 to 2021 were collected, registered, and analyzed by GraphPad Prism software. Results Totally 200 AD patients were registered in our database. 107 (54%) were women and age of 147 (74%) were over 65. The mean age for men and women was 76.20 ± 8.29 and 76.40 ± 8.83 years, respectively. 132 (66%) were married and 64 (32%) were illiterate. Also, 94 (47%) were in the moderate stage of disease, and 150 (75%) lived at home together with their families. The most frequent neurological comorbidity was psychosis (n = 72, 36%), while hypertension was the most common non‐neurological comorbidity (n = 104, 52%). The GDS score of women in the mild stage (5.23 ± 2.9 vs. 6.9 ± 2.6, p = 0.005) and moderate stage (5.36 ± 2.4 vs. 8.21 ± 2.06, p = 
ISSN:2398-8835
2398-8835
DOI:10.1002/hsr2.952