Effect of non-surgical periodontal treatment on clinical signs of rheumatoid arthritis

Background. Several studies have shown the association between periodontitis and rheumatoid arthritis (RA) and some similarities in the pathogenesis of these two diseases but clinical trials which have evaluated the effect of periodontal therapy on clinical signs of active RA are scarce, particularl...

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Bibliographic Details
Published in:Journal of advanced periodontology and implant dentistry 2018-10, Vol.10 (1), p.13-17
Main Authors: Atarbashi-Moghadam, Fazele, Rashidi Maybodi, Fahimeh, Dehghan, Ali, Haerian Ardakani, Alireza
Format: Article
Language:English
Subjects:
chronic periodontitis
non-surgical
periodontal treatment
rheumatoid arthritis
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Summary:Background. Several studies have shown the association between periodontitis and rheumatoid arthritis (RA) and some similarities in the pathogenesis of these two diseases but clinical trials which have evaluated the effect of periodontal therapy on clinical signs of active RA are scarce, particularly in Iran. The aim of this study was to evaluate the effect of non-surgical periodontal treatment on the improvement of clinical signs of patients with RA. Methods. Fifty-six patients with active RA and generalized moderate-to-severe chronic periodontitis were selected and divided into case (periodontal treatment) and control (without periodontal treatment) groups. Periodontal parameters and RA disease activity scores (DAS28 index) were compared at 6- and 12-week intervals. Results. In the case group, a significant reduction in all the periodontal indices was observed 6 weeks after treatment. At the 12-week evaluation, periodontal indices showed a significant reduction in comparison with baseline and a little increase in comparison with 6-week interval. Six weeks after treatment, DAS28 decreased significantly in the case group (P
ISSN:2645-5390
2645-5390
DOI:10.15171/japid.2018.003